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HomeProduct name listErythrodiol

Erythrodiol

Synonym(s):Olean-12-ene-3β,28-diol

  • CAS NO.:545-48-2
  • Empirical Formula: C30H50O2
  • Molecular Weight: 442.72
  • MDL number: MFCD00017294
  • EINECS: 208-890-4
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-19 23:02:33
Erythrodiol Structural

What is Erythrodiol?

Description

Erythrodiol is a triterpene that has been found in olive oil and has diverse biological activities. It induces relaxation of isolated rat aortic rings precontracted with phenylephrine (EC50 = 3.38 μM). Erythrodiol inhibits the growth of HT-29 adenocarcinoma cells (EC50 = 48.8 μM). It induces production of reactive oxygen species (ROS) and apoptosis in MCF-7 cells when used at a concentration of 100 μM. Topical administration of erythrodiol (0.5 mg/ear) reduces ear edema and myeloperoxidase (MPO) activity induced by phorbol 12-myristate 13-acetate (TPA; ) in mice.

The Uses of Erythrodiol

It is an essential reagent in the synthesis of aminopropoxytriterpenoids that have anticancer activity. 3β-Erythrodiol has pharmacological property as a vasodilatory agent. It may have interesting therapeutic potential as a new vasodilator drug, for protecting the cardiovascular system.

What are the applications of Application

Erythrodiol is A reference material for the analytical determination of olive oil

Definition

ChEBI: Erythrodiol is a pentacyclic triterpenoid that is beta-amyrin in which one of the hydrogens of the methyl group at position 28 has been replaced by a hydroxy group. It is a plant metabolite found in olive oil as well as in Rhododendron ferrugineum and other Rhododendron species. It has a role as a plant metabolite. It is a pentacyclic triterpenoid, a primary alcohol, a secondary alcohol and a diol. It is functionally related to a beta-amyrin.

Properties of Erythrodiol

Melting point: 230-231 °C(lit.)
Boiling point: 520.5±50.0 °C(Predicted)
Density  1.05±0.1 g/cm3(Predicted)
storage temp.  -20°C Freezer, Under inert atmosphere
solubility  Chloroform (Slightly, Sonicated), Methanol (Slightly)
form  Solid
pka 15.09±0.10(Predicted)
color  White to Off-White
Water Solubility  insoluble in water
BRN  2340203
CAS DataBase Reference 545-48-2(CAS DataBase Reference)

Safety information for Erythrodiol

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
Precautionary Statement Codes P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313:IF SKIN irritation occurs: Get medical advice/attention.
P337+P313:IF eye irritation persists: Get medical advice/attention.

Computed Descriptors for Erythrodiol

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