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HomeProduct name listPropylene glycol

Propylene glycol

Synonym(s):Propylene glycol;1,2-Propanediol;1,2-Propylene glycol;1,2-PDO;Propylene Glycol, 1

  • CAS NO.:57-55-6
  • Empirical Formula: C3H8O2
  • Molecular Weight: 76.09
  • MDL number: MFCD00064272
  • EINECS: 200-338-0
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-05-07 14:24:42
Propylene glycol Structural Picture

What is Propylene glycol?

Description

Propylene glycol is used as antifreeze in breweries and diaries, in the manufacture of resins, as a solvent, and as an emulsifier in food. It was present as an occupational sensitizer in the color-film developer Flexicolor.

The Uses of Propylene glycol

Next to water, propylene glycol is the most common moisturecarrying vehicle used in cosmetic formulations. It has better skin permeation than glycerin, and it also gives a pleasant feel with less greasiness than glycerin. Propylene glycol is used as a humectant because it absorbs water from the air. It also serves as a solvent for anti-oxidants and preservatives. In addition, it has preservative properties against bacteria and fungi when used in concentrations of 16 percent or higher. There is a concern that propylene glycol is an irritant at high concentrations, though it appears to be quite safe at usage levels under 5 percent.

Background

A clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations.

Metabolism

Not Available

Properties of Propylene glycol

Melting point: -60 °C (lit.)
Boiling point: 187 °C (lit.)
Density  1.036 g/mL at 25 °C (lit.)
Flash point: 225 °F
storage temp.  Store at +5°C to +30°C.
solubility  Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form  Viscous Liquid
color  APHA: ≤10
Water Solubility  miscible
Sensitive  Hygroscopic

Safety information for Propylene glycol

Signal word Danger
Pictogram(s)

Health Hazard
GHS08
GHS Hazard Statements H370:Specific target organ toxicity, single exposure
H372:Specific target organ toxicity, repeated exposure
Precautionary Statement Codes P260:Do not breathe dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P270:Do not eat, drink or smoke when using this product.
P405:Store locked up.

Computed Descriptors for Propylene glycol

InChIKey DNIAPMSPPWPWGF-UHFFFAOYSA-N

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