Eflornithine hydrochloride
Synonym(s):2-(Difluoromethyl)-DL -ornithine monohydrochloride monohydrate;Eflornithin monohydrochloride monohydrate
- CAS NO.：68278-23-9
- Empirical Formula: C6H13ClF2N2O2
- Molecular Weight: 218.63
- MDL number: MFCD00274036
- EINECS: 269-532-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-30 15:45:59
What is Eflornithine hydrochloride?
The Uses of Eflornithine hydrochloride
Antineoplastic; antiprotozoal.
The Uses of Eflornithine hydrochloride
DL-alpha-Difluoromethylornithine Hydrochloride is an irreversible inhibitor of ornithine decarboxylase.
What are the applications of Application
DL-α-Difluoromethylornithine hydrochloride is an irreversible inhibitor of ODC (ornithine decarboxylase)
Indications
Vaniqa (eflornithine hydrochloride 13.9%) cream is a unique topical cream that slows anagen hair growth by irreversibly blocking the enzyme ornithine decarboxylase. This enzyme produces polyamines in the hair matrix that are partially responsible for the growth of the anagen hair. The cream was tested only on the upper lip and chin region. The onset of action is usually within 8 weeks of starting the b.i.d. treatment, and the hair growth will return to baseline within 8 weeks of discontinuing the drug. Patients need to be reminded that this product does not remove hair but slows its growth in between whatever they use for hair removal.
brand name
Ornidyl (Sanofi Aventis); Vaniqa (Skinmedica).
storage
Desiccate at RT
Properties of Eflornithine hydrochloride
| Melting point: | 181-184°C |
| storage temp. | Store at -20°C |
| solubility | H2O: >10 mg/mL, soluble |
| form | solid |
| color | white |
| Water Solubility | Soluble to 75 mM in water |
| CAS DataBase Reference | 68278-23-9(CAS DataBase Reference) |
Safety information for Eflornithine hydrochloride
Computed Descriptors for Eflornithine hydrochloride
Eflornithine hydrochloride manufacturer
A.B.ENTERPRISES
Rusan Pharma Ltd
Sami Sabinsa Group Limited (formerly Sami Labs Limited)
AB Enterprises
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