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HomeProduct name listEflornithine hydrochloride

Eflornithine hydrochloride

Synonym(s):2-(Difluoromethyl)-DL-ornithine monohydrochloride monohydrate;Eflornithin monohydrochloride monohydrate

  • CAS NO.:68278-23-9
  • Empirical Formula: C6H13ClF2N2O2
  • Molecular Weight: 218.63
  • MDL number: MFCD00274036
  • EINECS: 269-532-0
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-06-30 15:45:59
Eflornithine hydrochloride Structural

What is Eflornithine hydrochloride?

The Uses of Eflornithine hydrochloride

Antineoplastic; antiprotozoal.

The Uses of Eflornithine hydrochloride

DL-alpha-Difluoromethylornithine Hydrochloride is an irreversible inhibitor of ornithine decarboxylase.

What are the applications of Application

DL-α-Difluoromethylornithine hydrochloride is an irreversible inhibitor of ODC (ornithine decarboxylase)

Indications

Vaniqa (eflornithine hydrochloride 13.9%) cream is a unique topical cream that slows anagen hair growth by irreversibly blocking the enzyme ornithine decarboxylase. This enzyme produces polyamines in the hair matrix that are partially responsible for the growth of the anagen hair. The cream was tested only on the upper lip and chin region. The onset of action is usually within 8 weeks of starting the b.i.d. treatment, and the hair growth will return to baseline within 8 weeks of discontinuing the drug. Patients need to be reminded that this product does not remove hair but slows its growth in between whatever they use for hair removal.

brand name

Ornidyl (Sanofi Aventis); Vaniqa (Skinmedica).

storage

Desiccate at RT

Properties of Eflornithine hydrochloride

Melting point: 181-184°C
storage temp.  Store at -20°C
solubility  H2O: >10 mg/mL, soluble
form  solid
color  white
Water Solubility  Soluble to 75 mM in water
CAS DataBase Reference 68278-23-9(CAS DataBase Reference)

Safety information for Eflornithine hydrochloride

Computed Descriptors for Eflornithine hydrochloride

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