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68278-23-9

68278-23-9 structural image
Product Name: Eflornithine hydrochloride
Formula: C6H13ClF2N2O2
Synonyms: 2-(Difluoromethyl)-DL-ornithine monohydrochloride monohydrate;Eflornithin monohydrochloride monohydrate
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COMPUTED DESCRIPTORS

Molecular Weight 218.63 g/mol
Hydrogen Bond Donor Count 4
Hydrogen Bond Acceptor Count 6
Rotatable Bond Count 5
Exact Mass 218.0633617 g/mol
Monoisotopic Mass 218.0633617 g/mol
Topological Polar Surface Area 89.3 Ų
Heavy Atom Count 13
Formal Charge 0
Complexity 166
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 1
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 2
Compound Is Canonicalized Yes

PRODUCT INTRODUCTION

description

Eflornithine Hydrochloride is the hydrochloride form of eflornithine, a difluoromethylated ornithine compound with antineoplastic activity. Eflornithine irreversibly inhibits ornithine decarboxylase, an enzyme required for polyamine biosynthesis, thereby inhibiting the formation and proliferation of tumor cells. Polyamines are involved in nucleosome oligomerization and DNA conformation, creating a chromatin environment that stimulates neoplastic transformation of cells. (NCI04)

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product:68278-23-9 / 70050-56-5 Eflornithine hydrochloride 98%

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AB Enterprises

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