DL-Lactide
Synonym(s):Lactide
- CAS NO.:95-96-5
- Empirical Formula: C6H8O4
- Molecular Weight: 144.13
- MDL number: MFCD00011685
- EINECS: 202-468-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-24 21:11:45
What is DL-Lactide?
Chemical properties
White crystalline powder
The Uses of DL-Lactide
DL-Lactide is used to produce 2-hydroxy-propionic acid 1-(1-phenyl-ethoxycarbonyl)-ethyl ester. It acts as an important raw material and an intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyes. It is involved in enzymatic alcoholysis to produce both alkyl (R)-lactates and alkyl (S,S)-lactyllactates.
The Uses of DL-Lactide
Enzymatic alcoholysis of this racemic lactide catalyzed by commercial Novozym® 435 produces both alkyl (R)-lactates and alkyl (S,S)-lactyllactates in good yield and high enantiopurity.
Definition
ChEBI: Lactide is a member of dioxanes.
General Description
3,6-Dimethyl-1,4-dioxane-2,5-dione (or rac-lactide), is the 50:50 racemic mixture of D- and L-Lactide. Rac-lactide is a lactone derived from lactic acid that has attracted great interest in academia and commercial applications, as it is derived from abundant renewable resources. Rac-lactide can be ready polymerized via ring-opening polymerization, using a variety of metal or organocatalysts, yielding poly(D,L-lactide). While the resulting polymer is generally amorphous, the use of stereospecific catalysts can lead to heterotactic PLA, which exhibits some degree of crystallinity.
Flammability and Explosibility
Non flammable
Properties of DL-Lactide
Melting point: | 116-119 °C |
Boiling point: | 142 °C8 mm Hg(lit.) |
Density | 1.186±0.06 g/cm3(Predicted) |
vapor pressure | 0.311Pa at 25℃ |
Flash point: | 180°C |
storage temp. | 2-8°C |
solubility | Soluble in chloroform and methanol. Slightly soluble in benzene. |
form | Crystalline Powder |
color | White |
Water Solubility | 16.3g/L at 20℃ |
Sensitive | Moisture Sensitive |
BRN | 82121 |
NIST Chemistry Reference | 1,4-Dioxane-2,5-dione, 3,6-dimethyl-(95-96-5) |
EPA Substance Registry System | 1,4-Dioxane-2,5-dione, 3,6-dimethyl- (95-96-5) |
Safety information for DL-Lactide
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H319:Serious eye damage/eye irritation |
Precautionary Statement Codes |
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for DL-Lactide
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Nomisma Healthcare Pvt Ltd
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