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HomeProduct name listD-Aspartic acid

D-Aspartic acid

Synonym(s):(R)-(−)-Aminosuccinic acid;(R)-2-Aminosuccinic acid

  • CAS NO.:1783-96-6
  • Empirical Formula: C4H7NO4
  • Molecular Weight: 133.1
  • MDL number: MFCD00063081
  • EINECS: 217-234-6
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-08-24 19:19:26
D-Aspartic acid Structural

What is D-Aspartic acid?

Chemical properties

White or almost white crystalline powder

The Uses of D-Aspartic acid

A non-essential amino acid found in food sources and dietary supplements. D-Aspartic acid's conjugate base D-aspartate has potential use as a a therapeutic agent in the treatment of schizophrenia-related symptoms.

The Uses of D-Aspartic acid

D-Aspartic acid modulates melatonin synthesis in the pineal gland.

What are the applications of Application

D-Aspartic acid is an endogenous agonist of the NMDA receptor

Definition

ChEBI: The D-enantiomer of aspartic acid.

Biological Activity

Endogenous NMDA receptor agonist with similar activity to the L-isomer (L-Aminosuccinic acid ). Also a non-metabolizable substrate for EAA uptake systems. Modulates melatonin synthesis in the pineal gland.

storage

Room temperature

Properties of D-Aspartic acid

Melting point: >300 °C(lit.)
Boiling point: 245.59°C (rough estimate)
alpha  -25.8 º (c=5, 5N HCl)
Density  1.66
refractive index  -25 ° (C=8, 50% HCl)
storage temp.  Keep in dark place,Inert atmosphere,Room temperature
solubility  Aqueous Acid (Sparingly)
form  Crystalline Powder
pka pK1: 1.89(0);pK2: 3.65;pK3: 9.60 (25°C)
color  White to off-white
optical activity [α]20/D 24°, c = 2.3 in 6 M HCl
Water Solubility  SOLUBLE
Merck  14,840
BRN  1723529
CAS DataBase Reference 1783-96-6(CAS DataBase Reference)
NIST Chemistry Reference D-aspartic acid(1783-96-6)

Safety information for D-Aspartic acid

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for D-Aspartic acid

InChIKey CKLJMWTZIZZHCS-UWTATZPHSA-N

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