D-Aspartic acid
Synonym(s):(R)-(−)-Aminosuccinic acid;(R)-2-Aminosuccinic acid
- CAS NO.：1783-96-6
- Empirical Formula: C4H7NO4
- Molecular Weight: 133.1
- MDL number: MFCD00063081
- EINECS: 217-234-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-20 11:41:24
What is D-Aspartic acid?
Chemical properties
White or almost white crystalline powder
The Uses of D-Aspartic acid
A non-essential amino acid found in food sources and dietary supplements. D-Aspartic acid's conjugate base D-aspartate has potential use as a a therapeutic agent in the treatment of schizophrenia-related symptoms.
The Uses of D-Aspartic acid
D-Aspartic acid modulates melatonin synthesis in the pineal gland.
What are the applications of Application
D-Aspartic acid is an endogenous agonist of the NMDA receptor
Definition
ChEBI: The D-enantiomer of aspartic acid.
Biological Activity
Endogenous NMDA receptor agonist with similar activity to the L-isomer (L-Aminosuccinic acid ). Also a non-metabolizable substrate for EAA uptake systems. Modulates melatonin synthesis in the pineal gland.
storage
Room temperature
Properties of D-Aspartic acid
| Melting point: | >300 °C(lit.) |
| Boiling point: | 245.59°C (rough estimate) |
| alpha | -25.8 º (c=5, 5N HCl) |
| Density | 1.66 |
| refractive index | -25 ° (C=8, 50% HCl) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | Aqueous Acid (Sparingly) |
| form | Crystalline Powder |
| pka | pK1: 1.89(0);pK2: 3.65;pK3: 9.60 (25°C) |
| color | White to off-white |
| optical activity | [α]20/D 24°, c = 2.3 in 6 M HCl |
| Water Solubility | SOLUBLE |
| Merck | 14,840 |
| BRN | 1723529 |
| CAS DataBase Reference | 1783-96-6(CAS DataBase Reference) |
| NIST Chemistry Reference | D-aspartic acid(1783-96-6) |
Safety information for D-Aspartic acid
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for D-Aspartic acid
| InChIKey | CKLJMWTZIZZHCS-UWTATZPHSA-N |
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