D-Biotin
Synonym(s):Biotin;Vitamin B7;Vitamin H;D-(+)-Biotin;D(+)-Biotin
- CAS NO.:58-85-5
- Empirical Formula: C10H16N2O3S
- Molecular Weight: 244.31
- MDL number: MFCD00005541
- EINECS: 200-399-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-05-16 10:38:43
What is D-Biotin?
Absorption
Systemic - approximately 50%
Toxicity
Prolonged skin contact may cause irritation.
The Uses of D-Biotin
vasodilator
Indications
For nutritional supplementation, also for treating dietary shortage or imbalance.
What are the applications of Application
D-(+)-Biotin is an important ubiquitous metabolism coenzyme
Background
A water-soluble, enzyme co-factor present in minute amounts in every living cell. It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, and milk.
Pharmacokinetics
Biotin is a water-soluble B-complex vitamin which is composed of an ureido ring fused with a tetrahydrothiophene ring, which attaches a valeric acid substituent at one of its carbon atoms. Biotin is used in cell growth, the production of fatty acids, metabolism of fats, and amino acids. It plays a role in the Kreb cycle, which is the process in which energy is released from food. Biotin not only assists in various metabolic chemical conversions, but also helps with the transfer of carbon dioxide. Biotin is also helpful in maintaining a steady blood sugar level. Biotin is often recommended for strengthening hair and nails. Consequenty, it is found in many cosmetic and health products for the hair and skin. Biotin deficiency is a rare nutritional disorder caused by a deficiency of biotin. Initial symptoms of biotin deficiency include: Dry skin, Seborrheic dermatitis, Fungal infections, rashes including erythematous periorofacial macular rash, fine and brittle hair, and hair loss or total alopecia. If left untreated, neurological symptoms can develop, including mild depression, which may progress to profound lassitude and, eventually, to somnolence; changes in mental status, generalized muscular pains (myalgias), hyperesthesias and paresthesias. The treatment for biotin deficiency is to simply start taking some biotin supplements. A lack of biotin in infants will lead to a condition called seborrheic dermatitis or "cradle cap". Biotin deficiencies are extremely rare in adults but if it does occur, it will lead to anemia, depression, hair loss, high blood sugar levels, muscle pain, nausea, loss of appetite and inflamed mucous membranes.
Metabolism
Properties of D-Biotin
Melting point: | 231-233 °C(lit.) |
Boiling point: | 573.6±35.0 °C(Predicted) |
Density | 1.2693 (rough estimate) |
storage temp. | -20°C |
solubility | H2O: 0.2 mg/mL Solubility increases with addition of 1 N NaOH. |
form | powder |
color | White crystalline powder or fine long needles |
Water Solubility | Soluble in hot water, dimethyl sulfoxide, alcohol and benzene. |
Sensitive | Light Sensitive |
Safety information for D-Biotin
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for D-Biotin
InChIKey | YBJHBAHKTGYVGT-ZKWXMUAHSA-N |
Abamectin manufacturer
Jigs Chemical ltd
JSK Chemicals
Meteoric Biopharmaceuticals Pvt. Ltd.
Supreem Pharmaceuticals Mysore Pvt Ltd
Suvan LifeSciences (formerly Sansh Biotech Pvt Ltd)
New Products
3-N-BOC-(S)-AMINO BUTYRONITRILE 4-Piperidinopiperidine 2-Methyl-4-nitrobenzoic acid 2-(4-bromophenyl)-2-methylpropanoic acid 4-Acetyl-2-methylbenzoicacid Acetyl-meldrum's acid Ethyl-4-Pyrazole carboxylate 2,6 Di acetylpyridine 2,6-Pyridinedimethanol 5,7-Dichloro-3H-Imidazo[4,5-B]Pyridine 5-Bromo-2-Methoxy-4-Methyl-3-Nitropyridine 2-Fluoro-5-Iodopyridine 2-Fluoro-5-Methylpyridine 2-Chloro-3-Bromo-5-Amiopyridine METHYL-4-(BUTYRYLAMINO)3-METHYL-5-NITROBENZOATE TRANS-CYCLOBUTANE-1,2- DICARBOXYLIC ACID 5-Nitro indazole R-(-)-5-(2-AMINO-PROPYL)-2-METHOXY-BENZENESULFONAMIDE 1,3-cyclohexanedione 4-Aminophenaethylalchol 3-NITRO-5-ACETYL IMINODIBENZYL (S)-(+)-4-BENZYL-2-OXAZOLIDINONE 4-FLUORO PHENYL MAGNESIUM BROMIDE 1.0 M IN THF 1-HYDROXY-4-METHYL6-(2,4,4-TRI METHYL PHENYL)-2-PYRIDONE MONO ETHANOL AMINE(PIROCTONE OLAMINE)Related products of tetrahydrofuran
You may like
-
58-85-5 98%View Details
58-85-5 -
Biotin 99%View Details
58-85-5 -
D(+)-Biotin 58-85-5 99%View Details
58-85-5 -
58-85-5 Biotin, 99% 99%View Details
58-85-5 -
D-Biotin 99%View Details
-
Biotin 98%View Details
58-85-5 -
Biotin 58-85-5 98%View Details
58-85-5 -
58-85-5 Biotin 98%View Details
58-85-5