(R)-(-)-2-Amino-3-methyl-1-butanol
Synonym(s):D -Valinol
- CAS NO.：4276-09-9
- Empirical Formula: C5H13NO
- Molecular Weight: 103.16
- MDL number: MFCD00064297
- EINECS: 217-975-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-29 14:36:51
What is (R)-(-)-2-Amino-3-methyl-1-butanol?
Chemical properties
white to light yellow crystal powde
The Uses of (R)-(-)-2-Amino-3-methyl-1-butanol
D-Valinol is used as a reagent in the synthesis of the HIV type 1 integrase inhibitor Elvitegravir (E509000). D-Valinol is also used in the preparation of novel 2-(alkylmorpholin-4-yl)-6-(3-fluoropyridin-4-yl)-pyrimidin-4(3H)-ones as orally active GSK-3β inhibitors for Alzheimer''s disease.
Properties of (R)-(-)-2-Amino-3-methyl-1-butanol
| Melting point: | 35-36 °C(lit.) |
| alpha | -16.5 º (c=10, EtOH) |
| Boiling point: | 189-190 °C(lit.) |
| Density | 0.931 g/mL at 20 °C(lit.) |
| refractive index | n |
| Flash point: | 194 °F |
| storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 12.82±0.10(Predicted) |
| form | Low Melting Crystals or Crystalline Mass |
| color | White to light yellow |
| optical activity | [α]20/D 16°, c = 10 in ethanol |
| Sensitive | Air Sensitive |
| BRN | 1719138 |
| CAS DataBase Reference | 4276-09-9(CAS DataBase Reference) |
Safety information for (R)-(-)-2-Amino-3-methyl-1-butanol
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P321:Specific treatment (see … on this label). P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for (R)-(-)-2-Amino-3-methyl-1-butanol
| InChIKey | NWYYWIJOWOLJNR-YFKPBYRVSA-N |
(R)-(-)-2-Amino-3-methyl-1-butanol manufacturer
Vijaya Pharma And Life Science
1Y
Phone:+918939866271
Whatsapp: +91-8939866271
product: 4276-09-9 98%
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