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HomeProduct name listD-Norleucine

D-Norleucine

Synonym(s):(R)-2-Aminocaproic acid;(R)-2-Aminohexanoic acid

  • CAS NO.:327-56-0
  • Empirical Formula: C6H13NO2
  • Molecular Weight: 131.17
  • MDL number: MFCD00008099
  • EINECS: 206-320-9
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-05-04 17:34:37
D-Norleucine Structural

What is D-Norleucine?

Chemical properties

white to off-white crystalline powder or flakes

The Uses of D-Norleucine

D-Norleucine is used for the synthesis of Thailandepsin B, a bicyclic depsipeptide histone deacetylase inhibitor.

Definition

ChEBI: D-norleucine is the D-enantiomer of 2-aminohexanoic acid. It is an enantiomer of a L-norleucine. It is a tautomer of a D-norleucine zwitterion.

Purification Methods

Crystallise norleucine from water or aqueous MeOH. [Huffman & Ingersoll J Am Chem Soc 73 3366 1951, Beilstein 4 III 1386, 4 IV 2628.]

Properties of D-Norleucine

Melting point: ≥300 °C
Boiling point: 234.0±23.0 °C(Predicted)
alpha  [α]D20 -23.0~-25.0゜ (c=4, HCl)
Density  1.1720 (estimate)
refractive index  -23 ° (C=4.5, 6mol/L HCl)
storage temp.  Keep in dark place,Inert atmosphere,Room temperature
form  powder to crystal
pka 2.55±0.24(Predicted)
color  White
Water Solubility  15.75g/L(19 ºC)
Merck  14,6706
BRN  1721749
CAS DataBase Reference 327-56-0(CAS DataBase Reference)

Safety information for D-Norleucine

Computed Descriptors for D-Norleucine

InChIKey LRQKBLKVPFOOQJ-RXMQYKEDSA-N

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