Cytidine 5’-monophosphate
Synonym(s):5′-CMP;5′-Cytidylic acid;C-5′-P;Cytidine 5′-monophosphate
- CAS NO.：63-37-6
- Empirical Formula: C9H14N3O8P
- Molecular Weight: 323.2
- MDL number: MFCD00006544
- EINECS: 200-556-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-29 18:21:28
What is Cytidine 5’-monophosphate?
Description
Cytidine 5'-monophosphate, also known as 5'-CMP, is a nucleotide that is used as a monomer in RNA. 5'-CMP is a key intermediate in the preparation of several nucleotide derivatives and is widely used in food and pharmaceutical industries.
Chemical properties
white crystalline powder
The Uses of Cytidine 5’-monophosphate
A constituent of nucleic acids. It was isolated from yeast nucleic acid.
The Uses of Cytidine 5’-monophosphate
Cytidine 5′-monophosphate has been used in Raman spectroscopy studies.
What are the applications of Application
Cytidine 5′-monophosphate is a nucleic acid constituent
Definition
ChEBI: A pyrimidine ribonucleoside 5'-monophosphate having cytosine as the nucleobase.
Biochem/physiol Actions
Cytidine 5′-monophosphate (CMP) is used as a substrate of uridine monophosphate (UMP)/cytidine monophosphate (CMP) kinase (EC 2.7.4.4) to form CDP which upon phosphorylation to CTP supports DNA and RNA biosynthesis.
Properties of Cytidine 5’-monophosphate
| Melting point: | ~222 °C (dec.) |
| Boiling point: | 678.1±65.0 °C(Predicted) |
| Density | 2.15±0.1 g/cm3(Predicted) |
| refractive index | 9.8 ° (C=1, 0.5mol/L Na2HPO4) |
| storage temp. | 2-8°C |
| solubility | Water (Slightly, Heated) |
| form | crystalline |
| pka | pK2:4.39(0);pK3:6.62(+1) (25°C) |
| color | White |
| Water Solubility | soluble |
| BRN | 46982 |
| InChI | InChI=1S/C9H14N3O8P/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18/h1-2,4,6-8,13-14H,3H2,(H2,10,11,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1 |
| CAS DataBase Reference | 63-37-6(CAS DataBase Reference) |
| EPA Substance Registry System | 5'-Cytidylic acid (63-37-6) |
Safety information for Cytidine 5’-monophosphate
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Cytidine 5’-monophosphate
| InChIKey | IERHLVCPSMICTF-JDNPWWSISA-N |
| SMILES | P(OC[C@H]1O[C@@H](N2C=CC(N)=NC2=O)[C@H](O)[C@@H]1O)(O)(O)=O |
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