Chloroacetamide

Synonym(s):2-Chloroacetamide

CAS NO.：79-07-2
Empirical Formula: C2H4ClNO
Molecular Weight: 93.51
MDL number: MFCD00008027
EINECS: 201-174-2
SAFETY DATA SHEET (SDS)
Update Date: 2025-01-03 14:13:18

What is Chloroacetamide?

Description

Chloroacetamide is a preservative used in several applications such as in cutting metalwork fluids, in paints or in glues. It can induce contact dermatitis in hairdressers, or in shoemakers when used as a leather preservative.

Chemical properties

white crystalline powder

The Uses of Chloroacetamide

2-Chloroacetamide is used as surface-active agent in home laundry, cleaning products & household formulated cleaners, other industrial uses, petroleum production, polymer processing.

The Uses of Chloroacetamide

A component of herbicidal mixtures of cellulose biosynthesis inhibitors with VLCFA inhibitors.

The Uses of Chloroacetamide

preservative in cosmetic and pharmaceutical creams, shampoos, bath lotions, etc.; preservative in glues, cooling fluids.

Flammability and Explosibility

Non flammable

Contact allergens

Chloroacetamide as a preservative is used in several applications as in cutting metalworking fluids, in paints or in glues. It can induce contact dermatitis in hairdressers or in shoemakers, being used as a leather preservative.

Safety Profile

Poison by ingestion, intravenous, and intraperitoneal routes. Mutation data reported. When heated to decomposition it emits very toxic Cland NOx. See also N-CHLOROACETAMIDE.

Purification Methods

Recrystallise the amide from acetone and dry it under vacuum over P2O5. [Beilstein 2 IV 490.]

Properties of Chloroacetamide

Melting point:	116-118 °C(lit.)
Boiling point:	224.5 °C
Density	0.84
vapor pressure	0.05 mm Hg ( 20 °C)
refractive index	1.4480 (estimate)
Flash point:	170 °C
storage temp.	Store below +30°C.
solubility	methanol: soluble1g/10 mL
form	Crystalline Powder
pka	14.69±0.40(Predicted)
color	White
PH	3.8-4.1 (40g/l, H2O, 20℃)
Water Solubility	Soluble in water(90g/L).
Merck	14,2110
BRN	878191
CAS DataBase Reference	79-07-2(CAS DataBase Reference)
NIST Chemistry Reference	Acetamide, 2-chloro-(79-07-2)
EPA Substance Registry System	Acetamide, 2-chloro- (79-07-2)

Safety information for Chloroacetamide

Signal word	Danger
Pictogram(s)	Skull and Crossbones Acute Toxicity GHS06 Health Hazard GHS08
GHS Hazard Statements	H301:Acute toxicity,oral H317:Sensitisation, Skin
Precautionary Statement Codes	P201:Obtain special instructions before use. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water.