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HomeProduct name listBrivudine

Brivudine

Synonym(s):BVdU

  • CAS NO.:69304-47-8
  • Empirical Formula: C11H13BrN2O5
  • Molecular Weight: 333.14
  • MDL number: MFCD00058585
  • EINECS: 1806241-263-5
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-19 20:33:22
Brivudine Structural

What is Brivudine?

Description

(E)-5-(2-Bromovinyl)-2'-deoxyuridine is an thymidine analogue and acts as an anti-viral by inhibiting DNA plymerase.

Chemical properties

White solid

The Uses of Brivudine

It is used as pharmaceutical intermediate.

The Uses of Brivudine

Brivudine is a nucloside analog which causes induction of neuronal differentiation in human reporter cell lines and adult stem cells. Anti-Herpes medication.

Background

Brivudine is used in the treatment of herpes zoster. Although not approved in the U.S. or Canada, it is approved in several European countries.

What are the applications of Application

Brivudine is an antiviral compound

Metabolism

Not Available

Properties of Brivudine

Melting point: 165°C
Density  1.7800 (rough estimate)
refractive index  1.6520 (estimate)
storage temp.  Inert atmosphere,2-8°C
solubility  DMSO (Slightly), Methanol (Slightly)
form  Solid
pka 8.37±0.10(Predicted)
color  Off-White
Water Solubility  Soluble in water and methanol.
Merck  14,1378

Safety information for Brivudine

Computed Descriptors for Brivudine

InChIKey ODZBBRURCPAEIQ-CXYVBZRVSA-N

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