Brivudine
Synonym(s):BVdU
- CAS NO.：69304-47-8
- Empirical Formula: C11H13BrN2O5
- Molecular Weight: 333.14
- MDL number: MFCD00058585
- EINECS: 1806241-263-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 20:33:22
What is Brivudine?
Description
(E)-5-(2-Bromovinyl)-2'-deoxyuridine is an thymidine analogue and acts as an anti-viral by inhibiting DNA plymerase.
Chemical properties
White solid
The Uses of Brivudine
Brivudine is a nucloside analog which causes induction of neuronal differentiation in human reporter cell lines and adult stem cells. Anti-Herpes medication.
The Uses of Brivudine
It is used as pharmaceutical intermediate.
Background
Brivudine is used in the treatment of herpes zoster. Although not approved in the U.S. or Canada, it is approved in several European countries.
What are the applications of Application
Brivudine is an antiviral compound
Metabolism
Not Available
Properties of Brivudine
| Melting point: | 165°C |
| Density | 1.7800 (rough estimate) |
| refractive index | 1.6520 (estimate) |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 8.37±0.10(Predicted) |
| color | Off-White |
| Water Solubility | Soluble in water and methanol. |
| Merck | 14,1378 |
Safety information for Brivudine
Computed Descriptors for Brivudine
| InChIKey | ODZBBRURCPAEIQ-CXYVBZRVSA-N |
Brivudine manufacturer
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