Tris(hydroxymethyl)nitromethane

Synonym(s):2-Hydroxymethyl-2-nitro-1,3-propanediol

CAS NO.：126-11-4
Empirical Formula: C4H9NO5
Molecular Weight: 151.12
MDL number: MFCD00007395
EINECS: 204-769-5
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-18 17:43:10

Tris(hydroxymethyl)nitromethane Structural

What is Tris(hydroxymethyl)nitromethane?

Chemical properties

Off-white to orange solid. It crystallizes as white crystals in the mixed solution of ethyl acetate and benzene. Soluble in alcohol, slightly soluble in benzene and other hydrocarbons. Solubility in water (20°C) 220g/100ml.

The Uses of Tris(hydroxymethyl)nitromethane

Tris(hydroxymethyl)nitromethane, is used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff. It is used as a primary and secondary intermediate.

Preparation

Tris(hydroxymethyl)nitromethane is prepared by the condensation of nitromethane and formaldehyde under basic conditions.

What are the applications of Application

Tris(hydroxymethyl)nitromethane is a bactericide and slimicide for use in cooling fluids, paper and pulp industry; as a curing agent for certain adhesives; viscositycontrolling agent in cosmetics.To inhibit bacterial growth in circulating industrial water systems, cutting oils, nonprotein glues and sizings.

General Description

Tris(hydroxymethyl)nitromethane undergoes crosslinking with hexamethylene diisocyanate to form monolithic energetic gels. It is an effective hardener for variety of tannin-based adhesives.

Hazard

Moderate fire risk. Irritant to skin and eyes.

Purification Methods

Crystallise it from CHCl3/ethyl acetate or ethyl acetate/*benzene. It is an acid and a 0.1M solution in H2O has pH 4.5. IRRITANT. [Beilstein 1 H 520.]

Properties of Tris(hydroxymethyl)nitromethane

Melting point:	160 °C (dec.) (lit.)
Boiling point:	273.1°C (rough estimate)
Density	1.5652 (rough estimate)
refractive index	1.4183 (estimate)
solubility	H2O: soluble220g/100ml at 20°C
pka	12.32±0.10(Predicted)
form	powder to lump
color	White to Almost white
Water Solubility	It is soluble in water.
Merck	14,9753
BRN	742427
CAS DataBase Reference	126-11-4(CAS DataBase Reference)
NIST Chemistry Reference	1,3-Propanediol, 2-(hydroxymethyl)-2-nitro-(126-11-4)
EPA Substance Registry System	2-(Hydroxymethyl)-2-nitro-1,3-propanediol (126-11-4)

Safety information for Tris(hydroxymethyl)nitromethane

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H412:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P273:Avoid release to the environment. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P501:Dispose of contents/container to..…