Benzyloxyacetyl chloride
- CAS NO.：19810-31-2
- Empirical Formula: C9H9ClO2
- Molecular Weight: 184.62
- MDL number: MFCD00010768
- EINECS: 629-534-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-09-25 17:15:13
What is Benzyloxyacetyl chloride?
Chemical properties
Colorless to yellow liquid
The Uses of Benzyloxyacetyl chloride
Benzyloxyacetyl chloride is a reagent used to construct substituted 2-azetidinones for further elaboration into annulated β-lactams. It is a commonly employed reagent for asymmetric synthesis of β-lactams. It is also used in preparation of (S)-3-(methylamino)-3-((R)-pyrrolidin-3-yl)propanenitrile, key intermediate in the preparation of fluoroquinolone antibiotic for respiratory tract infections, non-racemic helicene and β-lactams.
The Uses of Benzyloxyacetyl chloride
Commonly employed reagent for asymmetric synthesis of β-lactams.1,2
Properties of Benzyloxyacetyl chloride
| Melting point: | 120 °C (decomp) |
| Boiling point: | 84-87 °C/0.4 mmHg (lit.) |
| Density | 1.17 g/mL at 25 °C (lit.) |
| refractive index | n |
| Flash point: | >230 °F |
| storage temp. | 2-8°C |
| form | Powder or Cyrstals |
| color | White |
| Water Solubility | Reacts with water. |
| Sensitive | Moisture Sensitive |
| BRN | 1947363 |
| CAS DataBase Reference | 19810-31-2(CAS DataBase Reference) |
Safety information for Benzyloxyacetyl chloride
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05 |
| GHS Hazard Statements |
H314:Skin corrosion/irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P363:Wash contaminated clothing before reuse. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for Benzyloxyacetyl chloride
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