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HomeProduct name listBenzyloxyacetyl chloride

Benzyloxyacetyl chloride

  • CAS NO.:19810-31-2
  • Empirical Formula: C9H9ClO2
  • Molecular Weight: 184.62
  • MDL number: MFCD00010768
  • EINECS: 629-534-8
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-13 11:39:21
Benzyloxyacetyl chloride Structural

What is Benzyloxyacetyl chloride?

Chemical properties

Colorless to yellow liquid

The Uses of Benzyloxyacetyl chloride

Benzyloxyacetyl chloride is a reagent used to construct substituted 2-azetidinones for further elaboration into annulated β-lactams. It is a commonly employed reagent for asymmetric synthesis of β-lactams. It is also used in preparation of (S)-3-(methylamino)-3-((R)-pyrrolidin-3-yl)propanenitrile, key intermediate in the preparation of fluoroquinolone antibiotic for respiratory tract infections, non-racemic helicene and β-lactams.

The Uses of Benzyloxyacetyl chloride

Commonly employed reagent for asymmetric synthesis of β-lactams.1,2

Properties of Benzyloxyacetyl chloride

Melting point: 120 °C (decomp)
Boiling point: 84-87 °C/0.4 mmHg (lit.)
Density  1.17 g/mL at 25 °C (lit.)
refractive index  n20/D 1.523(lit.)
Flash point: >230 °F
storage temp.  2-8°C
form  Powder or Cyrstals
color  White
Water Solubility  Reacts with water.
Sensitive  Moisture Sensitive
BRN  1947363
CAS DataBase Reference 19810-31-2(CAS DataBase Reference)

Safety information for Benzyloxyacetyl chloride

Signal word Danger
Pictogram(s)
ghs
Corrosion
Corrosives
GHS05
GHS Hazard Statements H314:Skin corrosion/irritation
Precautionary Statement Codes P280:Wear protective gloves/protective clothing/eye protection/face protection.
P363:Wash contaminated clothing before reuse.
P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405:Store locked up.

Computed Descriptors for Benzyloxyacetyl chloride

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