Alvimopan
- CAS NO.:156053-89-3
- Empirical Formula: C25H32N2O4
- Molecular Weight: 424.53
- MDL number: MFCD25970564
- EINECS: 1312995-182-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-18 11:31:14
![Alvimopan Structural](https://img.chemicalbook.in/CAS/GIF/156053-89-3.gif)
What is Alvimopan?
Absorption
Alvimopan's high affinity for the peripheral mu-receptor leads to slower absorption dependent on dissociation from the receptor and subsequently low oral bioavailability of less than 7%.
The Uses of Alvimopan
flavenoid cytoprotective agent for the treatment of mucosal lesions
The Uses of Alvimopan
A peripheral μ-opioid receptor antagonist. Gastroprokinetic.
Definition
ChEBI: Alvimopan is a peptide.
What are the applications of Application
Alvimopan is a gastroprokinetic, peripheral μ-opioid receptor antagonist.
Background
Alvimopan is a peripherally acting μ opioid antagonist. It is used to avoid postoperative ileus following small or large bowel resection and accelerates the gastrointestinal recovery period.
Indications
Used to accelerate the time to upper and lower gastrointestinal recovery following partial large or small bowel resection surgery with primary anastomosis. Also investigated for use in the treatment of pain (acute or chronic).
Metabolism
Alvimopan is primarily metabolized by intestinal flora to an active metabolite although it has no clinically significant contribution to the effects of the drug.
Properties of Alvimopan
Melting point: | 200-204°C |
Boiling point: | 684.1±55.0 °C(Predicted) |
Density | 1.166±0.06 g/cm3(Predicted) |
storage temp. | 2-8°C |
solubility | DMSO (Slightly), Methanol (Slightly, Sonicated, Heated) |
form | Solid |
pka | 3.39±0.10(Predicted) |
color | White |
Safety information for Alvimopan
Computed Descriptors for Alvimopan
Abamectin manufacturer
New Products
5-bromo-1,4-dimethyl-3-nitropyridin-2(1H)-one 4-bromo-2-chloro-6-methylpyridine N2,N2-diethyl-6-methylpyridine-2,5-diamine 4-bromo-6-chloropicolinic acid 2-chloro-6-methylpyridin-4-amine 5-bromo-2-methoxy-4-methyl-3-nitropyridine 4-(PYRROLIDINOSULFONYLMETHYL) PHENYLHYDRAZINE .HCl 2-(2-Bromophenyl)propan-2-ol 1,1,1-Trifluoro-2-Isothiocyanatoethane 5-Chloro-1,3-Benzoxazole-2-Thiol 2-chloro-7-cyclopentyl-N,N-diMethyl-7H-pyrrolo[2,3-d]pyriMidine-6-carboxamide 5-Methyl-1,3,4-Oxathiazol-2-One SIDCHEM CM-05 Sidchem BT 20 Sidchem 715 Sidchem 730 SIDCHEM MB-05 SIDCHEM 1032 [Heavy metal trapper] PIMECROLIMUS TAUTOMER I CORTISONE HEMISUCCINATE Clindamycin Phosphate Sulfoxide S DELTA 6 HYDROCORTISONE HEMISUCCINATE CLINDAMYCIN 2,3-PALMITATE TACROLIMUS C4-EPIMER DIENE IMPURITYRelated products of tetrahydrofuran
![Moxifloxacin hydrochloride](https://img.chemicalbook.in/CAS/20180808/GIF/186826-86-8.gif)
![Gabapentin](https://img.chemicalbook.in/CAS/GIF/60142-96-3.gif)
![Pidotimod](https://img.chemicalbook.in/CAS/GIF/121808-62-6.gif)
![Rivaroxaban](https://img.chemicalbook.in/CAS/GIF/366789-02-8.gif)
![Diphenoxylate](https://img.chemicalbook.in/CAS/GIF/915-30-0.gif)
![Thalidomide](https://img.chemicalbook.in/CAS/GIF/50-35-1.gif)
![Methyl acetate](https://img.chemicalbook.in/CAS/GIF/79-20-9.gif)
![Tribenuron methyl](https://img.chemicalbook.in/CAS/GIF/101200-48-0.gif)
You may like
-
156053-89-3 Alvimopan 98%View Details
156053-89-3 -
Alvimopan CAS 156053-89-3View Details
156053-89-3 -
2634-33-5/1310-73-2 10%View Details
2634-33-5/1310-73-2 -
Sidchem 715 CMIT /MIT 1.5%View Details
55965-84-9 -
SIDCHEM BT 20 2634-33-5/1310-73-2 20%View Details
2634-33-5/1310-73-2 -
SIDCHEM CM-05 55965-84-9/ 2682-20-4 CMIT/MIT 2.5% / MIT 2.5%View Details
55965-84-9/ 2682-20-4 -
2634-33-5/1310-73-2 20%View Details
2634-33-5/1310-73-2 -
SIDCHEM 1032 [Heavy metal trapper] 32%View Details