alpha-Toluenesulfonyl chloride
Synonym(s):α-Toluenesulfonyl chloride
- CAS NO.：1939-99-7
- Empirical Formula: C7H7ClO2S
- Molecular Weight: 190.65
- MDL number: MFCD00007455
- EINECS: 217-717-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-12-18 14:15:30
What is alpha-Toluenesulfonyl chloride?
Chemical properties
almost white crystalline powder
The Uses of alpha-Toluenesulfonyl chloride
a-Toluenesulfonyl Chloride inhibits intracellular protein breakdown in the L1210 ascites leukemia in mouse. It also functions as a reagent for the protection of amino groups as benzylsulfonamides which can be cleaved off through reduction.
What are the applications of Application
Phenylmethanesulfonyl chloride is an aliphatic sulfonyl chloride
Synthesis Reference(s)
The Journal of Organic Chemistry, 16, p. 621, 1951 DOI: 10.1021/jo01144a013
Synthesis, p. 1203, 1992 DOI: 10.1055/s-1992-26333
General Description
Phenylmethanesulfonyl chloride is an aliphatic sulfonyl chloride. It reacts with triethylamine in methylene chloride or ether to yield trans-stilbene and cis diphenylethylene sulfone. Its reaction with 1,1-bis(diethylamino)ethane has been studied. Addition of phenylmethanesulfonyl chloride to 1,3-diphenyl-2-pyrrolidinopropene in the presence of water was studied.
Properties of alpha-Toluenesulfonyl chloride
| Melting point: | 92-94 °C(lit.) |
| Boiling point: | 120 °C / 10mmHg |
| Density | 1.3264 (estimate) |
| refractive index | 1.624-1.626 |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | soluble in Toluene |
| form | Crystalline Powder |
| color | Almost white |
| Water Solubility | decomposes |
| Sensitive | Moisture Sensitive |
| BRN | 972806 |
| CAS DataBase Reference | 1939-99-7(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzenemethanesulfonyl chloride(1939-99-7) |
| EPA Substance Registry System | Benzenemethanesulfonyl chloride (1939-99-7) |
Safety information for alpha-Toluenesulfonyl chloride
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05 |
| GHS Hazard Statements |
H314:Skin corrosion/irritation |
| Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P363:Wash contaminated clothing before reuse. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for alpha-Toluenesulfonyl chloride
| InChIKey | OAHKWDDSKCRNFE-UHFFFAOYSA-N |
alpha-Toluenesulfonyl chloride manufacturer
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product: alpha-Toluenesulfonyl chloride 1939-99-7 99%
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