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HomeProduct name listAdipic dihydrazide

Adipic dihydrazide

Synonym(s):Adipic dihydrazide;Hexanedioic acid dihydrazide

  • CAS NO.:1071-93-8
  • Empirical Formula: C6H14N4O2
  • Molecular Weight: 174.2
  • MDL number: MFCD00007614
  • EINECS: 213-999-5
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-12-18 14:08:52
Adipic dihydrazide Structural

What is Adipic dihydrazide?

Description

Adipic dihydrazide (ADH) is the most suitable hydrazide cross-linking agent, and ADH has been widely used in water-based paint emulsions in combination with diacetone acrylamide. ADH is weakly alkaline, and there is a possibility of agglomeration when solid ADH is added directly to the emulsion, so usually ADH should be dissolved in hot water before use.

Chemical properties

white to slightly yellow crystalline powder

The Uses of Adipic dihydrazide

Adipic dihydrazide is used as a formaldehyde scavenger and reacts with formaldehyde, thereby preventing the volatilizing of formaldehyde in the air. It is also employed as a paint additive and coating additive. It is also used as an intermediate. Further, it is used for cross-linking water-based emulsions and as a hardener for certain epoxy resins, which finds application in powder coating.

The Uses of Adipic dihydrazide

Adipic acid dihydrazide is a homobifunctional cross-linking reagent specific for aldehydes resulting in relatively stable hydrazone linkages. Adipic acid dihydrazide is typically, used in the linking of glycoproteins, such as antibodies, in a site specific fashion following periodate oxidation. Oxidation and coupling may conveniently be performed at pH 5.0 due to the low pKa of the hydrazide which avoids competition by primary amines.

Flammability and Explosibility

Non flammable

Properties of Adipic dihydrazide

Melting point: 180-182 °C (lit.)
Boiling point: 305.18°C (rough estimate)
Density  1.2297 (rough estimate)
vapor pressure  0Pa at 25℃
refractive index  1.6700 (estimate)
Flash point: 150 °C
storage temp.  -20°C
solubility  H2O: 100 mg/mL
form  Crystalline Powder
pka 12.93±0.35(Predicted)
color  White to slightly yellow
Water Solubility  soluble
BRN  973863
CAS DataBase Reference 1071-93-8(CAS DataBase Reference)
NIST Chemistry Reference Adipic dihydrazide(1071-93-8)
EPA Substance Registry System Hexanedioic acid, dihydrazide (1071-93-8)

Safety information for Adipic dihydrazide

Signal word Warning
Pictogram(s)
ghs
Environment
GHS09
GHS Hazard Statements H411:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes P273:Avoid release to the environment.
P391:Collect spillage. Hazardous to the aquatic environment
P501:Dispose of contents/container to..…

Computed Descriptors for Adipic dihydrazide

InChIKey IBVAQQYNSHJXBV-UHFFFAOYSA-N

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