Adenosine 3',5'-cyclic monophosphate sodium salt

Synonym(s):3′,5′-Cyclic AMP sodium salt;cAMP-Na

CAS NO.：37839-81-9
Empirical Formula: C10H13N5NaO6P
Molecular Weight: 353.21
MDL number: MFCD00069736
EINECS: 253-328-3
SAFETY DATA SHEET (SDS)
Update Date: 2024-09-20 17:27:21

Adenosine 3',5'-cyclic monophosphate sodium salt Structural

What is Adenosine 3',5'-cyclic monophosphate sodium salt?

Chemical properties

White crystalline powder

The Uses of Adenosine 3',5'-cyclic monophosphate sodium salt

Adenosine 3',5'-cyclic monophosphate sodium salt is an Adenosine (A280400) derivative useful as anticancer agent.

The Uses of Adenosine 3',5'-cyclic monophosphate sodium salt

Adenosine 3?,5?-cyclic monophosphate sodium salt monohydrate is used as an activator of protein kinase A (PKA) . A key regulator of many cellular reactions. Released in response to hormonal stimulation. . Directly activates Epac, a Rap1 guanine-nucleotide exchange factor. Acts as a second messenger in signal transduction mechanisms. Promotes apoptosis in resting human B lymphocytes.

What are the applications of Application

Adenosine 3′,5′-cyclic monophosphate sodium salt monohydrate is a PKA (protein kinase A) activator

Biochem/physiol Actions

Naturally-occurring activator of cyclic-AMP-dependent protein kinase (PKA). cAMP is an important second messenger that is linked in many systems to neurotransmitter- or hormone-induced receptor stimulation. The cAMP/PKA signaling pathway has been shown to inhibit cell proliferation, induce differentiation and lead to apoptosis.

Properties of Adenosine 3',5'-cyclic monophosphate sodium salt

storage temp.	-20°C
solubility	H₂O: 50 mg/mL
form	powder
color	white
Water Solubility	Soluble in water (50 mg/ml).
BRN	54612
Stability:	Hygroscopic
CAS DataBase Reference	37839-81-9

Safety information for Adenosine 3',5'-cyclic monophosphate sodium salt

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.