Adenosine-5'-diphosphate disodium salt
Synonym(s):5′-ADP-Na2
- CAS NO.:16178-48-6
- Empirical Formula: C10H15N5O10P2.2Na
- Molecular Weight: 471.16
- MDL number: MFCD00066635
- EINECS: 240-314-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-08 20:21:46
What is Adenosine-5'-diphosphate disodium salt?
Description
Adenosine-5'-diphosphate disodium salt is a sodium salt of adenosine 5'-diphosphate. Adenosine 5'-diphosphate disodium salt has been shown to inhibit the binding of serotonin (5-hydroxytryptamine) to 5-HT2 receptors, which are present in heart tissue.
Chemical properties
White crystalline powder
The Uses of Adenosine-5'-diphosphate disodium salt
Adenosine-5'-diphosphate disodium salt is an important raw material and intermediate used in organic synthesis, pharmaceuticals and agrochemicals.
What are the applications of Application
Adenosine 5′-Diphosphate disodium salt is an adenine nucleotide
What are the applications of Application
Adenosine-5'-diphosphate disodium salt is found in the extract of plants such as salvianolic acid and rhizoma gastrodiae, as well as in dinucleotide phosphate. This product has been shown to have cardioprotective effects against ischemia reperfusion injury in animal models. It also has congestive heart failure activity, which may be due to its ability to relax vascular smooth muscle and increase the diameter of lymphatic vessels.
Biochem/physiol Actions
Adenosine 5′-diphosphate (ADP) is an adenine nucleotide involved in energy storage and nucleic acid metabolism via its conversion into ATP by ATP synthases. ADP affects platelet activation through its interaction with purinergic receptors P2Y1 and P2Y12. Upon its conversion to adenosine by ecto-ADPases, platelet activation is inhibited via adenosine receptors.
Properties of Adenosine-5'-diphosphate disodium salt
storage temp. | -20°C |
form | Powder |
color | White |
optical activity | [α]20/D 29.6±1°, c = 0.5% in 0.5 M Na2HPO4 |
Water Solubility | Soluble in water. |
Sensitive | Hygroscopic |
BRN | 3645656 |
CAS DataBase Reference | 16178-48-6(CAS DataBase Reference) |
EPA Substance Registry System | Adenosine 5'-(trihydrogen diphosphate), disodium salt (16178-48-6) |
Safety information for Adenosine-5'-diphosphate disodium salt
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for Adenosine-5'-diphosphate disodium salt
InChIKey | AIZARHCNBKWDRW-KWIZKVQNSA-L |
SMILES | [Na+].[Na+].C(OP(=O)(O)OP(O)(O)=O)[C@H]1O[C@@H](N2C3C(=C(N=CN=3)N)N=C2)[C@H]([O-])[C@@H]1[O-] |
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