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HomeProduct name listAdenosine-5'-diphosphate disodium salt

Adenosine-5'-diphosphate disodium salt

Synonym(s):5′-ADP-Na2

  • CAS NO.:16178-48-6
  • Empirical Formula: C10H15N5O10P2.2Na
  • Molecular Weight: 471.16
  • MDL number: MFCD00066635
  • EINECS: 240-314-7
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-08 20:21:46
Adenosine-5'-diphosphate disodium salt Structural

What is Adenosine-5'-diphosphate disodium salt?

Description

Adenosine-5'-diphosphate disodium salt is a sodium salt of adenosine 5'-diphosphate. Adenosine 5'-diphosphate disodium salt has been shown to inhibit the binding of serotonin (5-hydroxytryptamine) to 5-HT2 receptors, which are present in heart tissue.

Chemical properties

White crystalline powder

The Uses of Adenosine-5'-diphosphate disodium salt

Adenosine-5'-diphosphate disodium salt is an important raw material and intermediate used in organic synthesis, pharmaceuticals and agrochemicals.

What are the applications of Application

Adenosine 5′-Diphosphate disodium salt is an adenine nucleotide

What are the applications of Application

Adenosine-5'-diphosphate disodium salt is found in the extract of plants such as salvianolic acid and rhizoma gastrodiae, as well as in dinucleotide phosphate. This product has been shown to have cardioprotective effects against ischemia reperfusion injury in animal models. It also has congestive heart failure activity, which may be due to its ability to relax vascular smooth muscle and increase the diameter of lymphatic vessels.

Biochem/physiol Actions

Adenosine 5′-diphosphate (ADP) is an adenine nucleotide involved in energy storage and nucleic acid metabolism via its conversion into ATP by ATP synthases. ADP affects platelet activation through its interaction with purinergic receptors P2Y1 and P2Y12. Upon its conversion to adenosine by ecto-ADPases, platelet activation is inhibited via adenosine receptors.

Properties of Adenosine-5'-diphosphate disodium salt

storage temp.  -20°C
form  Powder
color  White
optical activity [α]20/D 29.6±1°, c = 0.5% in 0.5 M Na2HPO4
Water Solubility  Soluble in water.
Sensitive  Hygroscopic
BRN  3645656
CAS DataBase Reference 16178-48-6(CAS DataBase Reference)
EPA Substance Registry System Adenosine 5'-(trihydrogen diphosphate), disodium salt (16178-48-6)

Safety information for Adenosine-5'-diphosphate disodium salt

Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.

Computed Descriptors for Adenosine-5'-diphosphate disodium salt

InChIKey AIZARHCNBKWDRW-KWIZKVQNSA-L
SMILES [Na+].[Na+].C(OP(=O)(O)OP(O)(O)=O)[C@H]1O[C@@H](N2C3C(=C(N=CN=3)N)N=C2)[C@H]([O-])[C@@H]1[O-]

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