6-Methoxyguanine
Synonym(s):2-Amino-6-methoxypurine;6-O-Methylguanine;6-Methoxyguanine
- CAS NO.:20535-83-5
- Empirical Formula: C6H7N5O
- Molecular Weight: 165.15
- MDL number: MFCD00133009
- EINECS: 606-576-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-08-17 21:30:02
What is 6-Methoxyguanine?
Chemical properties
Off-white solid
The Uses of 6-Methoxyguanine
Antitumor agent
The Uses of 6-Methoxyguanine
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
What are the applications of Application
6-O-Methylguanine is a methylated guanine with antitumor properties
Definition
ChEBI: A methylguanine in which the methyl group is positioned on the oxygen at position 6. Formed in DNA by alkylation of the oxygen atom of guanine, most often by N-nitroso compounds and sometimes due to methylation by other compounds such as endogenous S-adenosylmethionine, it base-pairs to thymine rather than cytidine, causing a G:C to A:T transition in DNA.
General Description
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
Properties of 6-Methoxyguanine
Melting point: | >300 °C(lit.) |
Boiling point: | 598.5±53.0 °C(Predicted) |
Density | 1.531±0.06 g/cm3(Predicted) |
storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
solubility | DMSO (Slightly, Heated), Water (Slightly, Heated) |
form | Solid |
pka | 9.74±0.10(Predicted) |
color | Off-White to Pale Yellow |
BRN | 645384 |
CAS DataBase Reference | 20535-83-5(CAS DataBase Reference) |
Safety information for 6-Methoxyguanine
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P501:Dispose of contents/container to..… |
Computed Descriptors for 6-Methoxyguanine
InChIKey | BXJHWYVXLGLDMZ-UHFFFAOYSA-N |
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