Tris(hydroxymethyl)aminomethane
Synonym(s):Tris;Tromethamine;Tris base;Trometamol;Tris(Hydroxymethyl)aminomethane
- CAS NO.:77-86-1
- Empirical Formula: C4H11NO3
- Molecular Weight: 121.14
- MDL number: MFCD00004679
- EINECS: 201-064-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-05-10 16:01:40
What is Tris(hydroxymethyl)aminomethane?
The Uses of Tris(hydroxymethyl)aminomethane
In the synthesis of surface-active agents, vulcanization accelerators, pharmaceuticals. As emulsifying agent for cosmetic creams and lotions, mineral oil and paraffin wax emulsions, leather dressings, textile specialties, polishes, cleaning Compounds, so-called soluble oils. Absorbent for acidic gases. Biological buffer.
Background
An organic amine proton acceptor. It is used in the synthesis of surface-active agents and pharmaceuticals; as an emulsifying agent for cosmetic creams and lotions, mineral oil and paraffin wax emulsions, as a biological buffer, and used as an alkalizer. (From Merck, 11th ed; Martindale, The Extra Pharmacopoeia, 30th ed, p1424)
Indications
For the prevention and correction of metabolic acidosis.
What are the applications of Application
Tris Base solution is a high-quality 1.5 M buffer solution containing 0.05% sodium azide as a preservative
What are the applications of Application
Tris base is widely used as a biological buffer or as a component of buffer formulations. Tris base has buffering capabilities in the pH range of 7.0-9.0.
Metabolism
Not Available
Properties of Tris(hydroxymethyl)aminomethane
Melting point: | 167-172 °C(lit.) |
Boiling point: | 219-220 °C10 mm Hg(lit.) |
Density | 1,353 g/cm3 |
Flash point: | 219-220°C/10mm |
storage temp. | 20-25°C |
solubility | H2O: 4 M at 20 °C, clear, colorless |
form | crystalline |
color | white |
Water Solubility | 550 g/L (25 ºC) |
Sensitive | Hygroscopic |
Safety information for Tris(hydroxymethyl)aminomethane
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Tris(hydroxymethyl)aminomethane
InChIKey | LENZDBCJOHFCAS-UHFFFAOYSA-N |
Abamectin manufacturer
RVR Labs Pvt Ltd
CHEMAZON LABORATORIES PRIVATE LIMITED
JSK Chemicals
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