5,6,7,8-Tetrahydro-1-naphthylamine

Synonym(s):1-Amino-5,6,7,8-tetrahydronaphthalene;5-Aminotetralin

CAS NO.：2217-41-6
Empirical Formula: C10H13N
Molecular Weight: 147.22
MDL number: MFCD00001736
EINECS: 218-713-2
SAFETY DATA SHEET (SDS)
Update Date: 2023-12-25 17:47:29

5,6,7,8-Tetrahydro-1-naphthylamine Structural

What is 5,6,7,8-Tetrahydro-1-naphthylamine?

Chemical properties

Clear yellow to brown liquid

The Uses of 5,6,7,8-Tetrahydro-1-naphthylamine

5,6,7,8-Tetrahydro-1-naphthylamine is used as a reagent in the synthesis of GoSlo-SR-5-69, a potent activator of large conductance Ca2+-activated K+ (BK) channels. 5,6,7,8-Tetrahydro-1-naphthylamine is also used as a reagent in the synthesis of benzopyrans and related compounds as inhibitors of the hypoxia inducible factor pathway.

Properties of 5,6,7,8-Tetrahydro-1-naphthylamine

Melting point:	38 °C(lit.)
Boiling point:	275-277 °C713 mm Hg(lit.)
Density	1,06 g/cm³
refractive index	n20/D 1.590(lit.)
Flash point:	>230 °F
solubility	miscible with Alcohol
form	Liquid
pka	4.56±0.20(Predicted)
color	Clear yellow to brown
BRN	387264
CAS DataBase Reference	2217-41-6(CAS DataBase Reference)
NIST Chemistry Reference	1-Naphthalenamine, 5,6,7,8-tetrahydro-(2217-41-6)

Safety information for 5,6,7,8-Tetrahydro-1-naphthylamine

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P501:Dispose of contents/container to..…