5-Sulfosalicylic acid dihydrate

Chemical properties

white crystalline powder

The Uses of 5-Sulfosalicylic acid dihydrate

5-Sulfosalicylic Acid Dihydrate is for reducing and fixation of proteins in agarose and polyacrylamide gels.

The Uses of 5-Sulfosalicylic acid dihydrate

5-Sulfosalicylic acid dihydrate may be used in the preparation of 1:1 proton-transfer organic adduct, 3-aminopyridin-ium 3-carb-oxy-4-hydroxy-benzene-sulfonate monohydrate and the anhydrous adduct.

What are the applications of Application

5-Sulfosalicylic acid dihydrate is for reducing and fixation of proteins in agarose and polyacrylamide gels

General Description

5-Sulfosalicylic acid is a strong acid capable of protonating water. It forms a new theophylline complex, which was investigated by X-ray photoelectron spectroscopy (XPS). It forms 1:1 proton-transfer compounds with the ortho-substituted monocyclic heteroaromatic Lewis bases. Their crystal structures have been studied.

Purification Methods

Crystallise the acid from H2O. Alternatively, it is converted to the monosodium salt which is crystallised from H2O and washed with a little H2O, EtOH and then Et2O. The acid is recovered by acidifying. The S-4-chlorobenzylisothiuronium salt has m 181o (from dioxane). [Beilstein 11 H 411, 11 II 232, 11 III 704.]