Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomeProduct name list4,5-Dimethylthiazole

4,5-Dimethylthiazole

  • CAS NO.:3581-91-7
  • Empirical Formula: C5H7NS
  • Molecular Weight: 113.18
  • MDL number: MFCD00005336
  • EINECS: 222-703-3
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-07-24 13:33:21
4,5-Dimethylthiazole Structural

What is 4,5-Dimethylthiazole?

Chemical properties

4,5-Dimethylthiazole is a colorless to light yellow liquid that has a roasted nutty, meaty, boiled poultry-like odor.

Occurrence

Reported found in peanuts, toasted oats, malt, peach, pork, coffee, krill, shrimp and scallops

The Uses of 4,5-Dimethylthiazole

4,5-Dimethylthiazole was used in the preparation of 4-(bromomethyl)-5-(dibromomethyl)thiazole.

Preparation

From methyl-α-bromoethyl ketone; by oxidation of 2-mercaptothiazoles with hydrogen peroxide in aqueous solution; from 2-mercapto-4,5-dimethylthiazole.

Definition

ChEBI: 4,5-Dimethylthiazole is a member of thiazoles.

Aroma threshold values

Detection: 470 ppb

Taste threshold values

Taste characteristics at 5 ppm: fishy, amine and pyridine-like with shrimp and savory nuances

Synthesis Reference(s)

The Journal of Organic Chemistry, 6, p. 764, 1941 DOI: 10.1021/jo01205a011

General Description

4,5-Dimethylthiazole is a thiazoles compounds that containing a thiazole ring substituted at positions 4 and 5 only. Radical bromination of 4,5-dimethylthiazole using N-bromosuccinimide in the presence of 2,2′-azobisisobutyronitrile yields mono-, tri- and tetrabromo compounds.

Properties of 4,5-Dimethylthiazole

Melting point: 83-84 C
Boiling point: 158 °C/742 mmHg (lit.)
Density  1.07 g/mL at 25 °C (lit.)
refractive index  n20/D 1.521(lit.)
FEMA  3274 | 4,5-DIMETHYLTHIAZOLE
Flash point: 124 °F
storage temp.  Sealed in dry,Room Temperature
form  solid
pka pK1:3.73 (25°C,μ=0.1)
Specific Gravity 1.070
Odor at 0.10 % in dipropylene glycol. roasted nutty fishy green boiled shrimp
JECFA Number 1035
BRN  105694
CAS DataBase Reference 3581-91-7(CAS DataBase Reference)
NIST Chemistry Reference Thiazole, 4,5-dimethyl-(3581-91-7)

Safety information for 4,5-Dimethylthiazole

Signal word Danger
Pictogram(s)
ghs
Flame
Flammables
GHS02
ghs
Corrosion
Corrosives
GHS05
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H226:Flammable liquids
H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H318:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233:Keep container tightly closed.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 4,5-Dimethylthiazole

Related products of tetrahydrofuran

You may like

Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.