4-Methylsalicylic acid

Synonym(s):m-Cresotic acid;2-Hydroxy-4-methylbenzoic acid

4-Methylsalicylic acid is white to greyish-beige powder

4-Methylsalicylic acid is similar to salicylic acid. Used in manufacturing of dyes.

4-Methylsalicylic acid was used to inhibit the medium chain acyl- CoA synthetase.

In manufacture of dyes.

4-Methylsalicylic acid is an inhibitor of ACSM (medium chain acyl-CoA synthetase)

4-Methylsalicylic acid is a monohydroxybenzoic acid consisting of salicylic acid having a methyl group at the 4-position.

The heteroleptic tris-cyclometalated iridium(III) complex with 4-methylsalicylic acid (Msal) was synthesized and characterized.

Crystallise the acid from water. It sublimes at 130o/11mm. [Beilstein 10 H 233, 10 II 137, 10 III 521, 10 IV 617.]

Melting point:	173-177 °C (lit.)
Boiling point:	234.6°C (rough estimate)
Density	1.2143 (rough estimate)
refractive index	1.4945 (estimate)
storage temp.	Inert atmosphere,Room Temperature
solubility	Chloroform (Slightly, Sonicated), DMSO (Slightly), Methanol (Slightly)
form	Powder
pka	pK1:3.17 (25°C)
color	White to grayish-beige
Water Solubility	Soluble in water 10 g/L @ 20℃.
Merck	14,2580
BRN	2208140
CAS DataBase Reference	50-85-1(CAS DataBase Reference)
NIST Chemistry Reference	2-Hydroxy-4-methylbenzoic acid(50-85-1)

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.