4-Chloro-3-nitrobenzoyl chloride

CAS NO.：38818-50-7
Empirical Formula: C7H3Cl2NO3
Molecular Weight: 220.01
MDL number: MFCD00035743
EINECS: 254-133-6
SAFETY DATA SHEET (SDS)
Update Date: 2023-05-15 10:43:14

What is 4-Chloro-3-nitrobenzoyl chloride?

Chemical properties

powder or crystals

The Uses of 4-Chloro-3-nitrobenzoyl chloride

4-Chloro-3-nitrobenzoyl chloride may be employed as acylation reagent for the Friedel-Crafts acylation of activated benzenes such as anisole, veratrole and 1,4-dimethoxybenzene. It may be employed for the synthesis of 4-chloro-4-methoxy-3-nitrobenzophenone. It may be employed as acylation reagent for the acylation reaction of the deactivated amines (2- aminopyrimidine, aminopyrazine).

General Description

4-Chloro-3-nitrobenzoyl chloride is an acid halide.

Properties of 4-Chloro-3-nitrobenzoyl chloride

Melting point:	47-54 °C(lit.)
Boiling point:	301.7±22.0 °C(Predicted)
Density	1.5741 (rough estimate)
refractive index	1.6140 (estimate)
Flash point:	230 °F
storage temp.	Inert atmosphere,2-8°C
solubility	Chloroform (Slightly)
color	White
Stability:	Stable, but may be air and moisture sensitive. Incompatible with strong oxidizing agents.
CAS DataBase Reference	38818-50-7(CAS DataBase Reference)
NIST Chemistry Reference	4-Chloro-3-nitrobenzoyl chloride(38818-50-7)

Safety information for 4-Chloro-3-nitrobenzoyl chloride

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05
GHS Hazard Statements	H314:Skin corrosion/irritation
Precautionary Statement Codes	P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P363:Wash contaminated clothing before reuse. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.