3-Nitrobenzyl chloride

Synonym(s):α-Chloro-3-nitrotoluene

CAS NO.：619-23-8
Empirical Formula: C7H6ClNO2
Molecular Weight: 171.58
MDL number: MFCD00007272
EINECS: 210-586-1
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

What is 3-Nitrobenzyl chloride?

Chemical properties

yellow to brown crystalline solid

The Uses of 3-Nitrobenzyl chloride

3-Nitrobenzyl chloride was used in the synthesis of 8-chloropurine.

General Description

Yellow to brown solid.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

A halogenated aromatic nitro compound. Aromatic nitro compounds range from slight to strong oxidizing agents. If mixed with reducing agents, including hydrides, sulfides and nitrides, they may begin a vigorous reaction that culminates in a detonation. The aromatic nitro compounds may explode in the presence of a base such as sodium hydroxide or potassium hydroxide even in the presence of water or organic solvents. The explosive tendencies of aromatic nitro compounds are increased by the presence of multiple nitro groups.

Fire Hazard

Flash point data concerning 3-Nitrobenzyl chloride are not available, however, 3-Nitrobenzyl chloride is probably combustible.

Purification Methods

Crystallise the chloride from pet ether (b 90-120o). IRRITANT.[Beilstein 5 IV 855.]

Properties of 3-Nitrobenzyl chloride

Melting point:	43-47 °C(lit.)
Boiling point:	85-87 °C5 mm Hg(lit.)
Density	1503
refractive index	1.5577 (estimate)
Flash point:	>230 °F
solubility	soluble in Methanol
form	Crystalline Solid
color	Light yellow to light brown
Water Solubility	<0.1 g/100 mL at 22 ºC
BRN	742794
CAS DataBase Reference	619-23-8(CAS DataBase Reference)
NIST Chemistry Reference	Benzene, 1-(chloromethyl)-3-nitro-(619-23-8)
EPA Substance Registry System	3-Nitrobenzyl chloride (619-23-8)

Safety information for 3-Nitrobenzyl chloride

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05
GHS Hazard Statements	H314:Skin corrosion/irritation
Precautionary Statement Codes	P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P363:Wash contaminated clothing before reuse. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.