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HomeProduct name list4-Chlorobenzyl chloride

4-Chlorobenzyl chloride

Synonym(s):α,4-Dichlorotoluene;(4-Chlorophenyl)methyl chloride;1-Chloro-4-(chloromethyl)benzene;NSC 34032

  • CAS NO.:104-83-6
  • Empirical Formula: C7H6Cl2
  • Molecular Weight: 161.03
  • MDL number: MFCD00000914
  • EINECS: 203-242-7
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-12-18 14:15:32
4-Chlorobenzyl chloride Structural

What is 4-Chlorobenzyl chloride?

Chemical properties

Colorless to light yellow liqui

The Uses of 4-Chlorobenzyl chloride

4-Chlorobenzyl Chloride is a benzylchloride derivative used in the preparation of various biologically active compounds such as bronchodilators and antibacterial agents.

The Uses of 4-Chlorobenzyl chloride

Reagent used in derivatization of, for example, a calix[4]arene1 and a tryptamine.2

The Uses of 4-Chlorobenzyl chloride

4-Chlorobenzyl chloride was the test compound for determining rat hepatocellular thiols by HPLC. As a reagent used in derivatization of, for example, a calix[4]arene and a tryptamine. It is widely used as an intermediate for manufacturing organic compounds like benzyl alcohol and benzyl cyanide. Also used in fuel as a gum inhibitor.

What are the applications of Application

4-Chlorobenzyl chloride is A reagent used in derivatization

General Description

4-Chlorobenzyl chloride is generally used in the preparation of quaternary ammonium salts. It acts as an intermediate in the production of rice herbicide, pharmaceuticals and pesticides.

Hazard

Irritating to skin, eyes.

Purification Methods

Dry it over CaSO4, then fractionally distil it under reduced pressure. Crystallise it from heptane or dry diethyl ether at low temperature. [Beilstein 5 IV 816.] LACHRYMATORY.

Properties of 4-Chlorobenzyl chloride

Melting point: 27-29 °C (lit.)
Boiling point: 216-222 °C (lit.)
Density  1.26
Flash point: 208 °F
refractive index  1.5575
storage temp.  Store at RT.
solubility  insoluble
form  Crystalline Low Melting Solid
Specific Gravity 1.26
color  Colorless to white
Water Solubility  insoluble
Sensitive  Lachrymatory
BRN  471558
Stability: Moisture Sensitive
CAS DataBase Reference 104-83-6(CAS DataBase Reference)
NIST Chemistry Reference Benzene, 1-chloro-4-(chloromethyl)-(104-83-6)
EPA Substance Registry System 4-Chlorobenzyl chloride (104-83-6)

Safety information for 4-Chlorobenzyl chloride

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
ghs
Environment
GHS09
GHS Hazard Statements H317:Sensitisation, Skin
H411:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P273:Avoid release to the environment.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

Computed Descriptors for 4-Chlorobenzyl chloride

4-Chlorobenzyl chloride manufacturer

LANXESS India Pvt. Ltd.

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