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HomeProduct name list3BETA-HYDROXY-5-CHOLESTENE 3-HEMISUCCINATE TRIS SALT

3BETA-HYDROXY-5-CHOLESTENE 3-HEMISUCCINATE TRIS SALT

Synonym(s):CHEMS;CHS;Cholesteryl hydrogen succinate;3β-Hydroxy-5-cholestene 3-hemisuccinate;3β-Hydroxy-5-cholestene 3-hemisuccinate; 5-Cholesten-3β-ol 3-hemisuccinate; CHS

3BETA-HYDROXY-5-CHOLESTENE 3-HEMISUCCINATE TRIS SALT Structural

What is 3BETA-HYDROXY-5-CHOLESTENE 3-HEMISUCCINATE TRIS SALT?

The Uses of 3BETA-HYDROXY-5-CHOLESTENE 3-HEMISUCCINATE TRIS SALT

Cholesteryl hemisuccinate tris salt has been used:

  • to prepare solubilization buffer for glucan synthase assay
  • to prepare immunoprecipitation buffer for immobilization of opioid receptors on paramagnetic beads.
  • as a membrane stabilizer for liposomes and protein synaptogyrin-1
  • as a component of a folate-modified self-microemulsifying drug delivery system.
  • with N-dodecyl β-D-maltoside (DDM) to solubilize erythrocyte ghosts and chemokine receptor CCR1
  • for protein solubilization

Biochem/physiol Actions

Cholesteryl hemisuccinate is an ionizable anionic detergent that stabilizes large unilamellar vesicles. These liposome vesicles act as delivery agents for anticancer drugs, oligonucleotides and antibiotics. Cholesteryl succinate also reportedly exhibits antiproliferative activity and may be clinically useful as antitumor agent.

Properties of 3BETA-HYDROXY-5-CHOLESTENE 3-HEMISUCCINATE TRIS SALT

storage temp.  -20°C

Safety information for 3BETA-HYDROXY-5-CHOLESTENE 3-HEMISUCCINATE TRIS SALT

Computed Descriptors for 3BETA-HYDROXY-5-CHOLESTENE 3-HEMISUCCINATE TRIS SALT

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