3BETA-HYDROXY-5-CHOLESTENE 3-HEMISUCCINATE TRIS SALT
Synonym(s):CHEMS;CHS;Cholesteryl hydrogen succinate;3β-Hydroxy-5-cholestene 3-hemisuccinate;3β-Hydroxy-5-cholestene 3-hemisuccinate; 5-Cholesten-3β-ol 3-hemisuccinate; CHS
- CAS NO.：102601-49-0
- Empirical Formula: C35H61NO7
- Molecular Weight: 607.87
- MDL number: MFCD00058298
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-12 15:22:20
What is 3BETA-HYDROXY-5-CHOLESTENE 3-HEMISUCCINATE TRIS SALT?
The Uses of 3BETA-HYDROXY-5-CHOLESTENE 3-HEMISUCCINATE TRIS SALT
Cholesteryl hemisuccinate tris salt has been used:
- to prepare solubilization buffer for glucan synthase assay
- to prepare immunoprecipitation buffer for immobilization of opioid receptors on paramagnetic beads.
- as a membrane stabilizer for liposomes and protein synaptogyrin-1
- as a component of a folate-modified self-microemulsifying drug delivery system.
- with N-dodecyl β-D-maltoside (DDM) to solubilize erythrocyte ghosts and chemokine receptor CCR1
- for protein solubilization
Biochem/physiol Actions
Cholesteryl hemisuccinate is an ionizable anionic detergent that stabilizes large unilamellar vesicles. These liposome vesicles act as delivery agents for anticancer drugs, oligonucleotides and antibiotics. Cholesteryl succinate also reportedly exhibits antiproliferative activity and may be clinically useful as antitumor agent.
Properties of 3BETA-HYDROXY-5-CHOLESTENE 3-HEMISUCCINATE TRIS SALT
| storage temp. | -20°C |
Safety information for 3BETA-HYDROXY-5-CHOLESTENE 3-HEMISUCCINATE TRIS SALT
Computed Descriptors for 3BETA-HYDROXY-5-CHOLESTENE 3-HEMISUCCINATE TRIS SALT
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