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HomeProduct name list3-Fluoro-4-methoxybenzeneboronic acid

3-Fluoro-4-methoxybenzeneboronic acid

Synonym(s):3-Fluoro-4-methoxybenzeneboronic acid;3-Fluoro-4-methyloxyphenylboronic acid;4-Methoxy-3-fluorophenylboronic acid

3-Fluoro-4-methoxybenzeneboronic acid Structural

What is 3-Fluoro-4-methoxybenzeneboronic acid?

Chemical properties

White solid

The Uses of 3-Fluoro-4-methoxybenzeneboronic acid

suzuki reaction

The Uses of 3-Fluoro-4-methoxybenzeneboronic acid

3-Fluoro-4-methoxyphenylboronic Acid is a useful reagent for regioselective Suzuki coupling reactions and other synthetic transformations.

The Uses of 3-Fluoro-4-methoxybenzeneboronic acid

Reactant for:

  • Preparation of hydroxyphenylnaphthols as 17?-hydroxysteroid dehydrogenase Type 2 inhibitors
  • Regioselective Suzuki coupling
  • Ruthenium-catalyzed arylation reactions
  • Synthesis of amino-trimethoxyphenyl-aryl thiazoles as microtubule inhibitors and potential antitumors
  • Rhodium catalyzed cyanation
  • Petasis reaction

General Description

Contains varying amounts of anhydride

Properties of 3-Fluoro-4-methoxybenzeneboronic acid

Melting point: 206-211 °C (lit.)
Boiling point: 318.1±52.0 °C(Predicted)
Density  1.26±0.1 g/cm3(Predicted)
storage temp.  Keep in dark place,Sealed in dry,Room Temperature
solubility  soluble in Methanol
form  powder
pka 7.87±0.10(Predicted)
color  White to Light yellow to Light orange
BRN  7370120
CAS DataBase Reference 149507-26-6(CAS DataBase Reference)

Safety information for 3-Fluoro-4-methoxybenzeneboronic acid

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405:Store locked up.

Computed Descriptors for 3-Fluoro-4-methoxybenzeneboronic acid

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