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HomeProduct name list3-Aminopropylphosphonic acid

3-Aminopropylphosphonic acid

3-Aminopropylphosphonic acid Structural

What is 3-Aminopropylphosphonic acid?

Chemical properties

Off-white to faintly greenish powder

The Uses of 3-Aminopropylphosphonic acid

3-Aminopropylphosphonic acid was used as a selective antagonist of GABA(C) receptor.

What are the applications of Application

3-Aminopropylphosphonic acid is a GABAB receptor agonist

Definition

ChEBI: (3-aminopropyl)phosphonic acid is a phosphonic acid in which the hydrogen attached to the phosphorus of phosphonic acid is substituted by a 3-aminopropyl group. It is a partial agonist of GABAB receptors. It has a role as a GABAB receptor agonist. It is a primary amino compound and a member of phosphonic acids. It is functionally related to a phosphonic acid. It is a tautomer of a (3-aminopropyl)phosphonic acid zwitterion.

General Description

The relative nonspecific binding of the DNA-conjugated gold nanoparticles (AuNPs) to the indium-tin oxide electrodes modified with 3-aminopropylphosphonic acid was examined by measuring the electrocatalytic anodic current of hydrazine caused by the nonspecifically absorbed AuNPs.

Biochem/physiol Actions

GABAB receptor agonist; antagonist of basal prolactin secretion.

Properties of 3-Aminopropylphosphonic acid

Melting point: 294 °C (dec.)(lit.)
Boiling point: 343.0±44.0 °C(Predicted)
Density  1.378±0.06 g/cm3(Predicted)
storage temp.  Keep in dark place,Inert atmosphere,Room temperature
solubility  DMF: 5 mg/ml; DMSO: 2 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/ml
pka 2.11±0.10(Predicted)
form  Powder
color  Off-white to faintly greenish
Water Solubility  soluble

Safety information for 3-Aminopropylphosphonic acid

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 3-Aminopropylphosphonic acid

InChIKey GSZQTIFGANBTNF-UHFFFAOYSA-N

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