EC 2.6.1.2

Synonym(s):L-Alanine: 2-Oxoglutarate Aminotransferase;Alanine Aminotransferase (catalytic concentration);GPT

CAS NO.：9000-86-6
Empirical Formula: C11H16N2O6
Molecular Weight: 272.25454
MDL number: MFCD00131192
EINECS: 232-561-4
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

What is EC 2.6.1.2?

The Uses of EC 2.6.1.2

It is used for research and clinical diagnostic assays for liver disease. Alanine transaminase (GPT/ALT) is used in multi-analyte clinical chemistry controls and calibrators for major IVD manufacturers. The alanine aminotransferase (ALT) blood test is typically used to detect liver injury. Some of the other applications include Diagnostic Controls, calibrators & standards, immunoassays, clinical chemistry, testing/assay validation, life Science, manufacturing, validation Studies.

General Description

Glutamic-pyruvic transaminase (GPT) is localized majorly in the liver.

Biochem/physiol Actions

Glutamic-pyruvic transaminase (GPT) mediates the transfer of the amino group to α-ketoglutarate from l-alanine. It plays a key role in gluconeogenesis and amino acid metabolism. The role of GPT in various kinds of tumors has been reported.

Properties of EC 2.6.1.2

storage temp.	-70°C
form	suspension (aqueous)
color	green-yellow
Water Solubility	Dissolves readily at 5 mg/ml in 0.05M potassium phosphate pH 7.5 to give a clear, pale-green solution. Soluble in distilled water or dilute buffer.
BRN	3562140
EPA Substance Registry System	Aminotransferase, alanine (9000-86-6)

Safety information for EC 2.6.1.2

Signal word	Danger
Pictogram(s)	Health Hazard GHS08
GHS Hazard Statements	H334:Sensitisation, respiratory
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P284:Wear respiratory protection. P501:Dispose of contents/container to..…