3-Acetylphenylboronic acid

CAS NO.：204841-19-0
Empirical Formula: C8H9BO3
Molecular Weight: 163.97
MDL number: MFCD01074678
EINECS: 629-232-6
SAFETY DATA SHEET (SDS)
Update Date: 2023-05-04 17:34:35

What is 3-Acetylphenylboronic acid?

Chemical properties

white to light yellow crystal powder

The Uses of 3-Acetylphenylboronic acid

3-Acetylphenylboronic acid can be used as a substrate:

In the synthesis of symmetric biaryls via oxidative dimerization using a palladium catalyst and water as a solvent.
In the synthesis of aryl fluorides through electrophilic fluorination reaction using acetyl hypofluorite.
In the coupling reactions of organoboranes with olefins using molecular oxygen and palladium catalyst.

Definition

ChEBI: 3-acetylphenylboronic acid is a member of the class of boronic acids that is phenylboronic acid substituted by an acetyl group at position 3. It is an aromatic ketone and a member of boronic acids. It is functionally related to a phenylboronic acid.

Properties of 3-Acetylphenylboronic acid

Melting point:	204-208 °C(lit.)
Boiling point:	364.0±44.0 °C(Predicted)
Density	1.19±0.1 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	DMSO (Slightly)
form	Crystalline Powder
pka	7.74±0.10(Predicted)
color	Light yellow
BRN	8255673
CAS DataBase Reference	204841-19-0(CAS DataBase Reference)

Safety information for 3-Acetylphenylboronic acid

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.