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HomeProduct name list2,4-Dichlorophenylboronic acid

2,4-Dichlorophenylboronic acid

Synonym(s):2,4-Dichlorobenzeneboronic acid

2,4-Dichlorophenylboronic acid Structural

What is 2,4-Dichlorophenylboronic acid?

Chemical properties

white to off-white powder

The Uses of 2,4-Dichlorophenylboronic acid

2,4-Dichlorophenylboronic acid is used as reactant involved in:
• Suzuki coupling reactions with alkynyl bromides or aniline / thiophenol
• Selective hydroxylation to phenols4Reactant involved in synthesis of biologically active molecules including:
• N-hydroxyindole-2-carboxylates for use as lactate dehydrogenase inhibitors
• Non-ATP competitive MK2 inhibitors

The Uses of 2,4-Dichlorophenylboronic acid

suzuki reaction

The Uses of 2,4-Dichlorophenylboronic acid

Reactant involved in:

  • Suzuki coupling reactions with alkynyl bromides or aniline / thiophenol
  • Selective hydroxylation to phenols

Reactant involved in synthesis of biologically active molecules including:
  • N-hydroxyindole-2-carboxylates for use as lactate dehydrogenase inhibitors
  • Non-ATP competitive MK2 inhibitors

Properties of 2,4-Dichlorophenylboronic acid

Melting point: 246-249 °C (lit.)
Boiling point: 331.3±52.0 °C(Predicted)
Density  1.47±0.1 g/cm3(Predicted)
storage temp.  Keep in dark place,Sealed in dry,Room Temperature
solubility  soluble in Methanol
form  Powder
pka 8.10±0.58(Predicted)
color  White to off-white
BRN  4983878
CAS DataBase Reference 68716-47-2(CAS DataBase Reference)

Safety information for 2,4-Dichlorophenylboronic acid

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405:Store locked up.

Computed Descriptors for 2,4-Dichlorophenylboronic acid

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