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HomeProduct name list2,3-Dichlorophenol

2,3-Dichlorophenol

Synonym(s):2,3-Dichlorophenol

  • CAS NO.:576-24-9
  • Empirical Formula: C6H4Cl2O
  • Molecular Weight: 163
  • MDL number: MFCD00002160
  • EINECS: 209-399-8
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-18 17:43:10
2,3-Dichlorophenol Structural

What is 2,3-Dichlorophenol?

Chemical properties

2,3-dichlorophenol appears as light brown crystalline solid. Soluble in ether, chloroform and hot ethanol, insoluble in water and benzene.

The Uses of 2,3-Dichlorophenol

2,3-Dichlorophenol is a chemical reagent used in the synthesis of a small molecule IL-2 inhibitor.

Preparation

2,3-Dichlorophenol is obtained from 1,2,3-trichlorobenzene by sulfonation to salt and high pressure hydrolysis to 3,4-dichloro-2-hydroxybenzenesulfonic acid, then hydrolyzed by sulfuric acid to remove the sulfonic acid group.

General Description

Brown crystals (from ligroin, benzene). Taste threshold concentration 0.00004 mg/L. Odor threshold concentration 0.03 mg/L.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

2,3-Dichlorophenol is incompatible with acid chlorides, acid anhydrides and oxidizing agents.

Fire Hazard

Flash point data for 2,3-Dichlorophenol are not available. 2,3-Dichlorophenol is probably combustible.

Purification Methods

Crystallise it from ether. [Beilstein 6 IV 883.]

Properties of 2,3-Dichlorophenol

Melting point: 56 °C
Boiling point: 214 °C
Density  1.40 g/cm3 (25℃)
refractive index  1.4430 (estimate)
Flash point: 115 °C
storage temp.  0-6°C
solubility  3600mg/l (experimental)
form  neat
pka 7.44(at 25℃)
color  White to Light red to Green
Water Solubility  <0.1 g/100 mL at 20 ºC
BRN  2043615
Stability: Stable. Incompatible with oxidizing agents, acid chlorides, acid anhydrides.
CAS DataBase Reference 576-24-9(CAS DataBase Reference)
NIST Chemistry Reference Phenol, 2,3-dichloro-(576-24-9)
EPA Substance Registry System 2,3-Dichlorophenol (576-24-9)

Safety information for 2,3-Dichlorophenol

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
Precautionary Statement Codes P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313:IF SKIN irritation occurs: Get medical advice/attention.
P337+P313:IF eye irritation persists: Get medical advice/attention.

Computed Descriptors for 2,3-Dichlorophenol

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