2-Thiopheneethanol

Synonym(s):2-(2-Hydroxyethyl)thiophene;2-(2-Thienyl)ethanol;2-(2-Thienyl)ethanol, 2-(2-Hydroxyethyl)thiophene;Thiophene-2-ethanol

CAS NO.：5402-55-1
Empirical Formula: C6H8OS
Molecular Weight: 128.19
MDL number: MFCD00005462
EINECS: 226-452-0
SAFETY DATA SHEET (SDS)
Update Date: 2024-08-14 18:30:21

What is 2-Thiopheneethanol?

Chemical properties

clear colorless to slightly brown liquid

The Uses of 2-Thiopheneethanol

2-Thiopheneethanol is a thiophene derivative used in the preparation of oligothiophene isothiocyanates as fluorescent markers for biopolymers. 2-Thiopheneethanol is also used in the preparation of oth er biologically active compounds such as the analgesic Sulfentanyl and the antithrombotic Clopidogrel Hydrogen Sulfate (C587250).

The Uses of 2-Thiopheneethanol

2-Thiopheneethanol, is used as the antithrombotics thiophene chlorine match piperidine intermediates. It is also used as a ticlopidine Intermediate.

Definition

ChEBI: 2-(2-Thienyl)ethanol is a heteroarene.

Synthesis Reference(s)

Journal of the American Chemical Society, 64, p. 477, 1942 DOI: 10.1021/ja01255a001
The Journal of Organic Chemistry, 59, p. 4323, 1994 DOI: 10.1021/jo00094a056

Properties of 2-Thiopheneethanol

Boiling point:	108-109 °C/13 mmHg (lit.)
Density	1.153 g/mL at 25 °C (lit.)
refractive index	n20/D 1.551(lit.)
Flash point:	214 °F
storage temp.	Store below +30°C.
solubility	Chloroform (Slightly), Ethyl Acetate (Slightly)
form	Liquid
pka	14.77±0.10(Predicted)
color	Clear light yellow to gray-green or brownish
Water Solubility	slightly soluble
BRN	106985
CAS DataBase Reference	5402-55-1(CAS DataBase Reference)
NIST Chemistry Reference	2-Thiopheneethanol(5402-55-1)
EPA Substance Registry System	2-Thiopheneethanol (5402-55-1)

Safety information for 2-Thiopheneethanol

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection.