2-Chloro-N-(2,6-dimethylphenyl)acetamide
Synonym(s):1-Chloroacetylamino-2,6-dimethylbenzene;2-Chloro-N-(2,6-dimethylphenyl)acetamide;2-Chloro-2′,6′-acetoxylidide;2-Chloro-2′,6′-dimethylacetanilide;Chloroacetamido-2,6-xylidine
- CAS NO.：1131-01-7
- Empirical Formula: C10H12ClNO
- Molecular Weight: 197.66
- MDL number: MFCD00000926
- EINECS: 214-460-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-11 22:00:27
What is 2-Chloro-N-(2,6-dimethylphenyl)acetamide?
Chemical properties
beige needles or crystalline powder
The Uses of 2-Chloro-N-(2,6-dimethylphenyl)acetamide
Lidocaine intermediate.
The Uses of 2-Chloro-N-(2,6-dimethylphenyl)acetamide
2-Chloro-2',6'-dimethylacetanilide is used in the determination of the enantiomers of tocainide in blood plasma by gas-liquid chromatography with electron-capture detection. It is a nonsteroidal antinflammatory drug.
General Description
N-(2,6-Dimethylphenyl)chloroacetamide (2-chloro-2′,6′-acetoxylidide) is nonsteroidal antinflammatory drug.
Properties of 2-Chloro-N-(2,6-dimethylphenyl)acetamide
| Melting point: | 150-151 °C(lit.) |
| Boiling point: | 316.8±30.0 °C(Predicted) |
| Density | 1.1363 (rough estimate) |
| refractive index | 1.5330 (estimate) |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| form | Crystalline Powder or Needles |
| pka | 12.91±0.70(Predicted) |
| color | White to brown |
| Water Solubility | Soluble in Chloroform, Methanol. Insoluble in water. |
| BRN | 781309 |
| Stability: | Light Sensitive |
| CAS DataBase Reference | 1131-01-7(CAS DataBase Reference) |
| NIST Chemistry Reference | 2-Chloro-2',6'-acetoxylidide(1131-01-7) |
| EPA Substance Registry System | Acetamide, 2-chloro-N-(2,6-dimethylphenyl)- (1131-01-7) |
Safety information for 2-Chloro-N-(2,6-dimethylphenyl)acetamide
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-Chloro-N-(2,6-dimethylphenyl)acetamide
| InChIKey | FPQQSNUTBWFFLB-UHFFFAOYSA-N |
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