1-Butylpyrrolidine
- CAS NO.:767-10-2
- Empirical Formula: C8H17N
- Molecular Weight: 127.23
- MDL number: MFCD00003184
- EINECS: 212-179-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-04-24 17:21:45
What is 1-Butylpyrrolidine?
The Uses of 1-Butylpyrrolidine
1-Butylpyrrolidine can be used in the composition for alcohol recovery solution.
The Uses of 1-Butylpyrrolidine
1-Butylpyrrolidine has been used in:
microwave-assisted synthesis of ionic liquid precursor, 1-butyl-1-methylpyrrolidinium methylcarbonate.
[N,N-methylbutylpyrrolidinium] thiosalicylate, ionic liquid.
The reaction of 1-butylpyrrolidine with dimethyl carbonate to yield the ionic liquid precursor, 1-butyl-1-methylpyrrolidinium methylcarbonate, has been investigated under microwave heating conditions and the reaction parameters optimised to achieve 100% yield of the pyrrolidinium salt with no by-products in under 1h.
Preparation
The synthesis of 1-butylpyrrolidine and its derivatives (1-butylpyrrolidine with a little of 1-butenylpyrrolidines) was developed via a one-pot method from ammonia and 1,4-butandiol. Here, the product of 1-butylpyrrolidine was emphatically investigated, and the yield was 76% under the optimized conditions. Such a route was realized through successive N-alkylation using aqueous ammonia as the nitrogen source over the CuNiPd/ZSM-5 catalyst, which was prepared by a simple incipient wetness method. In this route, 1,4-butandiol not only participated in the formation of the N-heterocycle, but also acted as an alkylating reagent. This work offers a straightforward, economical route for 1-butylpyrrolidine and its derivatives.
One-pot synthesis of 1-butylpyrrolidine and its derivatives from aqueous ammonia and 1,4-butandiol over CuNiPd/ZSM-5 catalysts
Properties of 1-Butylpyrrolidine
Boiling point: | 155-157 °C/754 mmHg (lit.) |
Density | 0.814 g/mL at 25 °C (lit.) |
refractive index | n |
Flash point: | 97 °F |
storage temp. | Refrigerator, Under inert atmosphere |
solubility | Chloroform (Sparingly), Ethyl Acetate (Slightly) |
form | Oil |
pka | 10.62±0.20(Predicted) |
color | Colourless |
CAS DataBase Reference | 767-10-2(CAS DataBase Reference) |
NIST Chemistry Reference | 1-Butylpyrrolidine(767-10-2) |
Safety information for 1-Butylpyrrolidine
Signal word | Danger |
Pictogram(s) |
Flame Flammables GHS02 Skull and Crossbones Acute Toxicity GHS06 |
GHS Hazard Statements |
H226:Flammable liquids |
Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. |
Computed Descriptors for 1-Butylpyrrolidine
New Products
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