TYRPHOSTIN AG 835
- CAS NO.：133550-37-5
- Empirical Formula: C18H16N2O3
- Molecular Weight: 308.33
- MDL number: MFCD00209855
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-07-12 17:17:45
What is TYRPHOSTIN AG 835?
The Uses of TYRPHOSTIN AG 835
Tyrphostin B44, (+) enantiomer is an EGFR kinase inhibitor.
What are the applications of Application
Tyrphostin B44, (+) enantiomer is an EGFR kinase inhibitor
Biological Activity
Epidermal growth factor receptor (EGFR) kinase inhibitor (IC 50 = 0.86 μ M). Slightly less active than the (-) enantiomer ((R)-(E)-2-Cyano-3-(3',4'-dihydroxyphenyl)-N-(1-phenylethyl)-2-propenamide ).
Properties of TYRPHOSTIN AG 835
| Melting point: | 146 °C |
| Boiling point: | 603.0±55.0 °C(Predicted) |
| Density | 1.299±0.06 g/cm3(Predicted) |
| storage temp. | −20°C |
| solubility | DMSO or ethanol: soluble |
| form | powder to crystal |
| pka | 8.81±0.10(Predicted) |
| color | Light yellow to Amber to Dark green |
Safety information for TYRPHOSTIN AG 835
| Signal word | Warning |
| Pictogram(s) |
 Health Hazard GHS08 |
| GHS Hazard Statements |
H371:Specific target organ toxicity, single exposure H373:Specific target organ toxicity, repeated exposure |
| Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P405:Store locked up. P501:Dispose of contents/container to..… |
Computed Descriptors for TYRPHOSTIN AG 835
New Products
2,2-diethoxyethanethioamide (R)-tert-butyl (4-methyl-1-oxopentan-3-yl)carbamate Tubulysin C Potassium HMDS (1.0 M in THF) 4-CYANO-TETRAHYDROPYRAN-4-CARBOXYLIC ACID 3-METHYLAZETIDIN-3-OL HYDROCHLORIDE 2-(azetidin-3-ylidene)acetonitrile (hydrochloride) 4,4-DIFLUOROPIPERIDINE 4-(Benzyloxy)-3-bromophenylacetic Acid 4,4-DIFLUOROCYCLOHEXANAMINE Fuel shell 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile Imeglimin Hydrochloride IH (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate Latanoprostene Bunod Lubiprostone Magnesium Trisilicate Flame Retardant Zinc Borate (R)-(3-(3-fluoro-4- thiomorpholinophenyl)-2- oxooxazolidin-4-yl) methyl methanesulfonate methyl 3-fluoro-4- thiomorpholino phenylcarbamate 7-Methoxyquinoline-4-carbonitrile 1H-Imidazole-4-carbonitrileRelated products of tetrahydrofuran
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