Triptorelin acetate
- CAS NO.:140194-24-7
- Empirical Formula: C64H82N18O13.C2H4O2
- Molecular Weight: 1371.52
- MDL number: MFCD14560565
- EINECS: 194-124-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-09-13 19:17:58
What is Triptorelin acetate?
Description
Triptorelin acetate (TA) is a GnRH agonist that was earlier used as a veterinary drug for a single fixed-time artificial insemination through the synchronised estrous cycle of weaned sows. The risk assessment was that the Food Safety Commission of Japan (FSCJ) concluded that TA is not likely to cause adverse effects on human health through dietary exposure. Because TA does not have genotoxicity relevant to human health and is degraded in the digestive tract, its oral bioavailability is low. TA is currently used for the treatment of central precocious puberty and assisted reproduction. Injectable TA alone or in combination with levonorgestrel intrauterine device is also used to treat endometrial atypical hyperplasia (EAH) . Combination therapy is more effective, improving patients' menstrual abnormalities, endometrial thickening and quality of life, and is safe.
Chemical properties
White Solid
The Uses of Triptorelin acetate
Synthetic peptide agonist analog of LH-RH. Triptoreline is a potent agonist of LH-releasing hormone, currently used in the treatment of prostatic cancer where therapy may be required over months or years. Antineoplastic (hormonal). Used in the treatment of endometriosis and infertility.
The Uses of Triptorelin acetate
Synthetic peptide agonist analog of LH-RH. Triptorelin acetate is a potent agonist of LH-releasing hormone, currently used in the treatment of prostatic cancer where therapy may be required over months or years. Antineoplastic (hormonal). Used in the treatment of endometriosis and infertility.
What are the applications of Application
Triptorelin Acetate is decreases pituitary secretion of gonadotropins luteinizing hormone (LH) and follicle stimulating hormone (FSH)
Properties of Triptorelin acetate
solubility | Aqueous Base (Slightly), Methanol (Very Slightly, Heated, Sonicated), Water (Slightly) |
form | Solid |
color | White to Off-White |
Stability: | Hygroscopic |
Safety information for Triptorelin acetate
Computed Descriptors for Triptorelin acetate
InChIKey | HPPONSCISKROOD-UXTGTKPXNA-N |
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