Trimagnesium dicitrate

Absorption

Mean plasma concentration of magnesium after administration of oral doses of magnesium citrate are reported to be of around 0.7 mmol/L and the concentration in saliva rested in 0.28 mmol/L. In reports, it has also been proven that the absorption and bioavailability of magnesium are greater when administered in the form of magnesium citrate when compared with other forms such as magnesium ocude.

Toxicity

The occurrence of overdose with magnesium citrate is very unlikely but some of the signs of the presence of overdose are diarrhea or severe stomach pain.

Chemical properties

White or slightly yellow granules powder

The Uses of Trimagnesium dicitrate

Trimagnesium Dicitrate is used in preparation of Cyclopentadiene Magnesium Ferrite nano material

The Uses of Trimagnesium dicitrate

Laxative .

Indications

Magnesium citrate has been used in bowel preparations prior to a colonoscopy as a cathartic agent.
It is also used in over-the-counter products to relieve occasional constipation.
Magnesium citrate can be one of the forms used for the administration of dietary supplements.

Background

Magnesium citrate is a low volume and osmotic cathartic agent. The cathartic action works primarily through the high osmolarity of the solution which draws large amounts of fluid into space where is used. Magnesium citrate is considered by the FDA as an approved inactive ingredient for approved drug products under the specifications of oral administration of a maximum concentration of 237 mg. It is also considered as an active ingredient in over-the-counter products.

Definition

ChEBI: A magnesium salt composed of magnesium and citrate ions in a 3:2 ratio.

Flammability and Explosibility

Non flammable

Pharmacokinetics

The onset of action can be as early as 30 minutes after administration with a mean onset time of approximately 2 hours and a maximum action of 4 hours. The effect of magnesium citrate is highly dependent on the individual's hydration status.

Metabolism

Not Available