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HomeProduct name listtrans-Ferulic acid

trans-Ferulic acid

Synonym(s):trans-4-Hydroxy-3-methoxycinnamic acid;trans-Ferulic acid;Ferulic acid

  • CAS NO.:537-98-4
  • Empirical Formula: C10H10O4
  • Molecular Weight: 194.18
  • MDL number: MFCD00004400
  • EINECS: 208-679-7
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-20 17:10:30
trans-Ferulic acid Structural

What is trans-Ferulic acid?

Chemical properties

solid

The Uses of trans-Ferulic acid

trans-Ferulic acid was used for esterification of methacrylated dextran. It was also used to study the effect of oral administration of trans-ferulic acid to c57BL mice on ethanol-induced liver injury. Furthermore, it has been used in the synthesis of new biocompatible antioxidant polymers linking trans-ferulic acid.

The Uses of trans-Ferulic acid

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Definition

ChEBI: Ferulic acid is a ferulic acid consisting of trans-cinnamic acid bearing methoxy and hydroxy substituents at positions 3 and 4 respectively on the phenyl ring. It has a role as an antioxidant, a MALDI matrix material, a plant metabolite, an anti-inflammatory agent, an apoptosis inhibitor and a cardioprotective agent. It is a conjugate acid of a ferulate.

Biochem/physiol Actions

Hydroxycinnamic acid found in plant-based foods. Antioxidant.

Description

Trans-Ferulic acid (TFA) is a derivative of hydroxyl cinnamic acid and is abundant in foods, fruits and beverages. Many studies have proven the effectiveness of this compound as an antioxidant, anti-inflammatory and antimicrobial agent.

Ecology

Trans-Ferulic acid is one of the compounds that initiate the vir (virulence) region of Agrobacterium tumefaciens, inducing it to infect plant cells.

Purification Methods

Crystallise ferulic acid from H2O. [Beilstein 10 H 436, 10 IV 1776.]

Properties of trans-Ferulic acid

Melting point: 168-172 °C(lit.)
Boiling point: 250.62°C (rough estimate)
Density  1.316(20.0000℃)
refractive index  1.5030 (estimate)
Flash point: 150℃
storage temp.  Store below +30°C.
solubility  DMSO (Slightly), Methanol (Slightly)
form  powder
pka 4.58±0.10(Predicted)
color  slightly yellow
Water Solubility  Soluble in alcohol and hot water.
Merck  14,4062
BRN  1371483
Stability: Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference 537-98-4(CAS DataBase Reference)
NIST Chemistry Reference 2-Propenoic acid, 3-(4-hydroxy-3-methoxyphenyl)-, (e)-(537-98-4)

Safety information for trans-Ferulic acid

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for trans-Ferulic acid

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