trans-Ferulic acid
Synonym(s):trans-4-Hydroxy-3-methoxycinnamic acid;trans-Ferulic acid;Ferulic acid
- CAS NO.:537-98-4
- Empirical Formula: C10H10O4
- Molecular Weight: 194.18
- MDL number: MFCD00004400
- EINECS: 208-679-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-20 17:10:30
What is trans-Ferulic acid?
Chemical properties
solid
The Uses of trans-Ferulic acid
trans-Ferulic acid was used for esterification of methacrylated dextran. It was also used to study the effect of oral administration of trans-ferulic acid to c57BL mice on ethanol-induced liver injury. Furthermore, it has been used in the synthesis of new biocompatible antioxidant polymers linking trans-ferulic acid.
The Uses of trans-Ferulic acid
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Definition
ChEBI: Ferulic acid is a ferulic acid consisting of trans-cinnamic acid bearing methoxy and hydroxy substituents at positions 3 and 4 respectively on the phenyl ring. It has a role as an antioxidant, a MALDI matrix material, a plant metabolite, an anti-inflammatory agent, an apoptosis inhibitor and a cardioprotective agent. It is a conjugate acid of a ferulate.
Biochem/physiol Actions
Hydroxycinnamic acid found in plant-based foods. Antioxidant.
Description
Trans-Ferulic acid (TFA) is a derivative of hydroxyl cinnamic acid and is abundant in foods, fruits and beverages. Many studies have proven the effectiveness of this compound as an antioxidant, anti-inflammatory and antimicrobial agent.
Ecology
Trans-Ferulic acid is one of the compounds that initiate the vir (virulence) region of Agrobacterium tumefaciens, inducing it to infect plant cells.
Purification Methods
Crystallise ferulic acid from H2O. [Beilstein 10 H 436, 10 IV 1776.]
Properties of trans-Ferulic acid
Melting point: | 168-172 °C(lit.) |
Boiling point: | 250.62°C (rough estimate) |
Density | 1.316(20.0000℃) |
refractive index | 1.5030 (estimate) |
Flash point: | 150℃ |
storage temp. | Store below +30°C. |
solubility | DMSO (Slightly), Methanol (Slightly) |
form | powder |
pka | 4.58±0.10(Predicted) |
color | slightly yellow |
Water Solubility | Soluble in alcohol and hot water. |
Merck | 14,4062 |
BRN | 1371483 |
Stability: | Stable. Incompatible with strong oxidizing agents. |
CAS DataBase Reference | 537-98-4(CAS DataBase Reference) |
NIST Chemistry Reference | 2-Propenoic acid, 3-(4-hydroxy-3-methoxyphenyl)-, (e)-(537-98-4) |
Safety information for trans-Ferulic acid
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for trans-Ferulic acid
Abamectin manufacturer
PEE ESS AROMATICS
AVIGYABIOSCIENCES PRIVATE LIMITED
New Products
4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium THOMAIND PAPER PH 2.0 TO 4.5 1 BOX BUFFER CAPSULE PH 9.2 - 10 CAP SODIUM CHLORIDE 0.1N CVS ALLOXAN MONOHYDRATE 98% PLATINUM 0.5% ON 3 MM ALUMINA PELLETS (TYPE 73) LITHIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
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