TRANS-4,5-DIHYDROXY-1,2-DITHIANE

Synonym(s):trans-1,2-Dithiane-4,5-diol;Oxidized DTT

CAS NO.：14193-38-5
Empirical Formula: C4H8O2S2
Molecular Weight: 152.24
MDL number: MFCD00006661
EINECS: 238-047-6
SAFETY DATA SHEET (SDS)
Update Date: 2023-05-04 17:34:33

TRANS-4,5-DIHYDROXY-1,2-DITHIANE Structural

What is TRANS-4,5-DIHYDROXY-1,2-DITHIANE?

The Uses of TRANS-4,5-DIHYDROXY-1,2-DITHIANE

trans-4,5-Dihydroxy-1,2-dithiane is used in preparation of 1,2-Dithiolane compounds useful in neuroprotection, autoimmune and cancer diseases and conditions.

What are the applications of Application

trans-4,5-Dihydroxy-1,2-dithiane is also known as Oxidized DTT

Definition

ChEBI: (4S,5S)-1,2-dithiane-4,5-diol is a trans-1,2-dithiane-4,5-diol. It is an enantiomer of a (4R,5R)-1,2-dithiane-4,5-diol.

General Description

trans-4,5-Dihydroxy-1,2-dithiane (oxidized dtt) is an intramolecular disulfide form of dithiothreitol. It is a strong reducing agent with an ability to elicit a molecular stress response by activating the stress-responsive genes.

Properties of TRANS-4,5-DIHYDROXY-1,2-DITHIANE

Melting point:	130-132 °C(lit.)
Boiling point:	284.9±40.0 °C(Predicted)
Density	1.531±0.06 g/cm3(Predicted)
storage temp.	2-8°C
pka	13.28±0.40(Predicted)

Safety information for TRANS-4,5-DIHYDROXY-1,2-DITHIANE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.