Temocapril hydrochloride

Description

Temocapril is a novel ACE inhibitor marketed in Japan for the treatment of hypertension. Temocapril is three times more potent than enalapril by oral administration, and has a long duration of action. It is characterized by a rapid onset of action resulting from a fast conversion of temocapril to the active metabolite diacid. Unlike most ACE inhibitors which are excreted mainly through the kidneys, temocapril is excreted predominantly through the biliary route indicating that temocapril is especially useful for treating hypertensive patients with renal dysfunction. The potential usefulness of temocapril in the treatment of congestive heart failure has been reported.

Chemical properties

White To Off-White Solid

Originator

Sankyo (Japan)

The Uses of Temocapril hydrochloride

Angiotensin-converting enzyme (ACE) inhibitor. Hydrolyzed in vivo to the active diacid metabolite

The Uses of Temocapril hydrochloride

angiotensin-converting enzyme inhibitor (ACE-I)

The Uses of Temocapril hydrochloride

Angiotensin-converting enzyme (ACE) inhibitor. Hydrolyzed in vivo to the active diacid metabolite.

What are the applications of Application

Temocapril Hydrochloride is an ACE inhibitor

Definition

ChEBI: Temocapril hydrochloride is a dipeptide.

brand name

Acecol