Temocapril hydrochloride
- CAS NO.：110221-44-8
- Empirical Formula: C23H28N2O5S2.ClH
- Molecular Weight: 513.076
- MDL number: MFCD00933433
- EINECS: 1312995-182-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-18 11:30:59
What is Temocapril hydrochloride?
Description
Temocapril is a novel ACE inhibitor marketed in Japan for the treatment of hypertension. Temocapril is three times more potent than enalapril by oral administration, and has a long duration of action. It is characterized by a rapid onset of action resulting from a fast conversion of temocapril to the active metabolite diacid. Unlike most ACE inhibitors which are excreted mainly through the kidneys, temocapril is excreted predominantly through the biliary route indicating that temocapril is especially useful for treating hypertensive patients with renal dysfunction. The potential usefulness of temocapril in the treatment of congestive heart failure has been reported.
Chemical properties
White To Off-White Solid
Originator
Sankyo (Japan)
The Uses of Temocapril hydrochloride
Angiotensin-converting enzyme (ACE) inhibitor. Hydrolyzed in vivo to the active diacid metabolite.
The Uses of Temocapril hydrochloride
Angiotensin-converting enzyme (ACE) inhibitor. Hydrolyzed in vivo to the active diacid metabolite
The Uses of Temocapril hydrochloride
angiotensin-converting enzyme inhibitor (ACE-I)
What are the applications of Application
Temocapril Hydrochloride is an ACE inhibitor
Definition
ChEBI: Temocapril hydrochloride is a dipeptide.
brand name
Acecol
Properties of Temocapril hydrochloride
| Melting point: | 196-2000C (dec) |
| alpha | 25D +47.7° (c = 1 in DMF) |
| storage temp. | Inert atmosphere,Store in freezer, under -20°C |
| solubility | DMF (Slightly), DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| color | White to Off-White |
| CAS DataBase Reference | 110221-44-8(CAS DataBase Reference) |
Safety information for Temocapril hydrochloride
Computed Descriptors for Temocapril hydrochloride
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