Tebuconazole

Chemical properties

White Solid

The Uses of Tebuconazole

Tebuconazole used as a seed dressing is effective against various smut and bunt diseases of cereals. Used as a spray it controls numerous pathogens in various crops: rust species, powdery mildew, Rhyncosporum secalis, Sqtoria spp., Pyrenophora spp., Fusarium spp. in cereals, Mycosphaerella spp. in bananas, Pucciniu spp. and Sclerufium roIfsii in peanuts.

The Uses of Tebuconazole

Ergosterol biosynthesis inhibitor. Fungicide.

The Uses of Tebuconazole

A triazole fungicide showing potential carcinogenicity

The Uses of Tebuconazole

Fungicide.

What are the applications of Application

Tebuconazole is a triazole fungicide showing potential carcinogenicity

Definition

ChEBI: 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol is a tertiary alcohol that is pentan-3-ol substituted by a 4-chlorophenyl, methyl, methyl, and a 1H-1,2,4-triazol-1-ylmethyl at positions 1, 4, 4 and 3 respectively. It is a member of monochlorobenzenes, a member of triazoles and a tertiary alcohol.

Agricultural Uses

Fungicide, Plant growth regulator: Used as a seed treatment against smuts and bunts of cereals; as a foliar spray against diseases of cereal, peanuts, oilseed rape, grapes, bananas, stone fruit, and pome fruit. Registered for use in EU countries. Registered for use in the U.S.

Trade name

BAY®-HWG 1608; BAYER®-HWG-1608 CORAIL®; ELITE®; FOLICUR®; FOLITRAZOLE®; GAUCHO®; HORIZON®; HWG 1608®; LYNX-1.2®; PREVENTOL® RAXIL (tebuconazole + metalaxyl); SILVACUR®; TEBUJECT®; WOLMAN®; WOODLIFE®

Metabolic pathway

Tebuconazole is degraded in soils and does not accumulate. In plants the metabolites were mainly compounds containing triazole, and in mammals tebuconazole was rapidly metabolised and excreted in urine and faeces.

Degradation

Tebuconazole is stable to elevated temperatures. Under sterile conditions it is stable to hydrolysis in water. It is hydrolysed slowly with a DTS0 of >1 year.
Only two products were formed by irradiation of a suspension of tebuconazole in water with UV light (>280 nm). These were the hydrochloride (3) and 1,2,4-triazole (2). The expected product in which chlorine was replaced by hydroxyl could not be isolated. In organic solvents a number of products were formed. Several products (3, 4, 5, 6, 7, 8, 9, 12, 13, 14) were isolated from benzene after 72 hours irradiation (>280 nm). In a number of cases products isolated from photolysis in benzene were formed by reactions in which the solvent participated and involved addition of a benzene molecule (4, 9, 5, 6). On irradiation in methylene chloride and methanol, 4-chloracetophenone (10) and acetophenone (11) were also identified in addition to starting material and 1,2,4-triazole (Wamhoff et al., 1994).