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HomeProduct name listSwertiamarine

Swertiamarine

Synonym(s):(4aR,5R,6S)-5-Ethenyl-6-(β-D-glucopyranosyloxy)-4,4a,5,6-tetrahydro-4a-hydroxy1H,3H-pyrano[3,4-c]pyran-1-one;4,4a,5,6-Tetrahydro-4aα-hydroxy-1-oxo-5β-vinyl-1H,3H-pyrano[3,4-c]pyran-6-yl β-D-glucopyranoside;Swertiamarin;Swertiamarine;Swertiamaroside

Swertiamarine Structural

What is Swertiamarine?

The Uses of Swertiamarine

Swertimarine is an extract from Enicostemma littorale which is an herb used in the treatment of type 1 and 2 diabetes. Used to sensitize the cells to hypolipidemic conditions and insulin.

Definition

ChEBI: Swertiamarin is a glycoside.

Properties of Swertiamarine

Melting point: 113-114°
Boiling point: 649.3±55.0 °C(Predicted)
alpha  D20 -127° (c = 1 in 96% ethanol)
Density  1.57±0.1 g/cm3(Predicted)
storage temp.  Sealed in dry,Store in freezer, under -20°C
solubility  DMSO : 250 mg/mL (667.84 mM; Need ultrasonic)
form  neat
pka 11.56±0.60(Predicted)
form  Solid
color  White to Yellow to Orange
λmax 238nm(MeOH)(lit.)
Merck  14,9010
BRN  55278
Stability: Hygroscopic
CAS DataBase Reference 17388-39-5(CAS DataBase Reference)

Safety information for Swertiamarine

Signal word Danger
Pictogram(s)
ghs
Corrosion
Corrosives
GHS05
ghs
Skull and Crossbones
Acute Toxicity
GHS06
ghs
Health Hazard
GHS08
ghs
Environment
GHS09
GHS Hazard Statements H301:Acute toxicity,oral
H314:Skin corrosion/irritation
H317:Sensitisation, Skin
H351:Carcinogenicity
H410:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes P201:Obtain special instructions before use.
P202:Do not handle until all safety precautions have been read and understood.
P260:Do not breathe dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P270:Do not eat, drink or smoke when using this product.
P272:Contaminated work clothing should not be allowed out of the workplace.
P273:Avoid release to the environment.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P391:Collect spillage. Hazardous to the aquatic environment
P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P308+P313:IF exposed or concerned: Get medical advice/attention.
P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention.
P405:Store locked up.

Computed Descriptors for Swertiamarine

InChIKey HEYZWPRKKUGDCR-QBXMEVCASA-N

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