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HomeProduct name listRhodamine 6G

Rhodamine 6G

Synonym(s):Basic Red 1;Rhodamine 6 G

  • CAS NO.:989-38-8
  • Empirical Formula: C28H31ClN2O3
  • Molecular Weight: 479.02
  • MDL number: MFCD00012665
  • EINECS: 213-584-9
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-19 20:33:22
Rhodamine 6G Structural

What is Rhodamine 6G?

Description

Rhodamine 6G is one the most effective laser dyes in recovering latent prints on various non-porous surfaces. This dye is normally used on non-porous surfaces, but may, under certain conditions, be used on porous or semi-porous surfaces. Rhodamine 6G is extremely efficient as it is highly fluorescent and can be used with various alternate light sources.
Rhodamine 6G has been used as a leukocyte marker to study the interaction between leukocytes and the vascular endothelium. It has also been used to label platelets.

Description

Rhodamine 6G is a fluorescent molecule—it gives off a specific wavelength of light when excited by light of a different wavelength. 6G was once used in dye lasers, but it is now used to detect biological compounds at the single molecule level.

Chemical properties

dark reddish purple, brown or black crystalline solid

The Uses of Rhodamine 6G

Rhodamine 6G has been used as a leukocyte marker to study the interaction between leukocytes and the vascular endothelium. It has also been used to label platelets.

The Uses of Rhodamine 6G

Rhodamine 6G (R6G) is an organic laser dye and can be used to study the probes as it has a high quantum yield for fluorescence. It can be used as a fluorescence tracker which helps in defining the spectroscopic characteristics for achieving a high conversion efficiency and precision of measurements. The absorption of R6G in different solvents can range between 400-700 nm.

The Uses of Rhodamine 6G

Rhodamine dyes are used extensively in biotechnology applications such as?fluorescence microscopy,?flow cytometry,fluorescence correlation spectroscopy?and?ELISA.

What are the applications of Application

Rhodamine 6G is a rhodamine analog potentially useful in Pgp efflux assays

Preparation

3-(Ethylamino)-4-methylphenol and Phthalic anhydride to afford the product was obtained ethanol and an inorganic acid esterification; O-Methylaniline with ethylene oxide Alkylation , sulfonated, alkali fusion, and Phthalic anhydride condensation, and then use ethylene oxide esterification.

Definition

Rhodamine 6G is a rhodamine 6G(1+), an organic chloride salt and a xanthene dye. It has a role as a fluorochrome.

What are the applications of Application

R6G can be used as a cationic dye to determine the photocatalytic ability of TiO2 reinforced graphene oxide composites that can be potentially used in self-cleaning applications. It can be used to calculate the quantum yield of glutathione-capped copper nanoclusters (CuNCs) for fluorescent thermo-responsive nanomaterials and gold nanoparticles (AuNPs) for fluorescent/X-ray computed tomography.

General Description

Bright bluish-pink crystals or reddish purple powder.

Air & Water Reactions

Insoluble in water.

Health Hazard

ACUTE/CHRONIC HAZARDS: When heated to decomposition Basic Red 1 emits very toxic fumes.

Fire Hazard

Flash point data for Basic Red 1 are not available. Basic Red 1 is probably combustible.

Flammability and Explosibility

Not classified

Biological Activity

Rhodamine 6G is a rhodamine analog useful in P-glycoprotein (Pgp) efflux assays. It has been used to characterize kinetics of multidrug resistance protein 1 (MRP1)-mediated efflux.
A rhodamine analog useful in Pgp efflux assays. Has been used to characterize kinetics of MRP1- mediated efflux.

Biochem/physiol Actions

Rhodamine 6G is a rhodamine analog useful in P-glycoprotein (Pgp) efflux assays. It has been used to characterize kinetics of multidrug resistance protein 1 (MRP1)-mediated efflux.

Safety Profile

Poison by ingestion and intraperitoneal routes. An experimental teratogen. Mutation data reported. Questionable carcinogen with experimental tumorigenic data. When heated to decomposition it emits very toxic fumes of Cland NOx.

Purification Methods

Crystallise the dye from MeOH or EtOH, and dry it in a vacuum oven. [Beilstein 18 III/IV 8244, 18/12 V 283.]

Properties and Applications

bright blue light pink. Purple powder or flash of green light crystallization. Soluble in water for big red, with strong green fluorescent, soluble in ethanol for red, with the yellow fluorescence. In the thick of the acid is yellow, diluted in red. Dye with sodium hydroxide solution with a red precipitate. Mainly used in the manufacture of color break, used in ink. Can also be used for cotton, wool and silk dyeing.

Standard( Silk ) Light Fastness Persperation Fastness Ironing Fastness Soaping
Fading Stain Fading Stain Fading Stain
ISO 2 4-5 1 3 3-4

Properties of Rhodamine 6G

Melting point: 215 °C
Density  1.26
vapor pressure  0Pa at 25℃
storage temp.  room temp
solubility  H2O: soluble1mg/mL, dark red
form  Powder
Colour Index  45160
color  Red-brown to brown
Odor Odorless
PH Range 6
Water Solubility  SOLUBLE
λmax 528 nm
BRN  3900071
Stability: Stable. Incompatible with strong oxidizing agents.
Biological Applications Detecting nucleic acids,prostate cancer,stress biomarkers,protease activity,urogenital infection; measuring membrane potential; photodynamic therapy; apoptosis assays; stents
Major Application Clays; colored bubbles; color filters; detergents; drawing materials; dye lasers;electroluminescent (EL) displays; glass materials; inks; laser devices/laser materials; light-emitting diode devices/materials; liquid crystals;liquid crystal displays; luminescent materials; metal oxide particles; petroleum products;photographic materials;photoresists; photovoltaic devices; polymer films; printing materials;recording materials; silica gel;solar cells;sol–gel materials; sputtered gold films;textiles; thin films;toners; tracers for hydrology;waveguides
CAS DataBase Reference 989-38-8(CAS DataBase Reference)
IARC 3 (Vol. 16, Sup 7) 1987
EPA Substance Registry System C.I. Basic Red 1 (989-38-8)

Safety information for Rhodamine 6G

Signal word Danger
Pictogram(s)
ghs
Corrosion
Corrosives
GHS05
ghs
Skull and Crossbones
Acute Toxicity
GHS06
ghs
Environment
GHS09
GHS Hazard Statements H301:Acute toxicity,oral
H317:Sensitisation, Skin
H318:Serious eye damage/eye irritation
H410:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P273:Avoid release to the environment.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for Rhodamine 6G

InChIKey VYXSBFYARXAAKO-BXMGYBSLSA-N

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