FUCHSIN BASIC

Description

Fuchsine, also known as rosaniline hydrochloride and magenta I, is one of the many coal-tar dyes synthesized by Emil and Otto Fischer; they first reported it in 1878. Even though it displays a magenta color when dissolved in water, its crystals are lustrous metallic green.

Chemical properties

Green crystal powder

The Uses of FUCHSIN BASIC

As a dye or in manufacture of other dyes.

The Uses of FUCHSIN BASIC

Biological stain for distinguishing coli and aerogene bacteriaBasic Fuchsin is useful for Ziehl-Neelson staining to detect acid-fast bacilli. It is also used to stain tubercle bacillus and bacterial flagella. It plays an important role for tissue sections to visualize elastic fibers, cardiac and skeletal muscle tissue. It also acts as bacterial and histological stains. Further, it is used to stain cellular elements, certain tissues, bacteria and also acts as a local anti-infective.

What are the applications of Application

Basic Fuchsin is a flourescent dye used for stainning and for the Ziel-Neelson staining method

Definition

ChEBI: A hydrochloride that is the monohydrochloride of 4-[(4-aminophenyl)(4-iminocyclohexa-2,5-dien-1-ylidene)methyl]-2-methylaniline. One of the major constituents of Basic fuchsin, together with pararosanilin, magenta II and new fuchsin.

General Description

Dark green powder. A dye derived from triphenylmethane.

Air & Water Reactions

Slightly soluble in water.

Reactivity Profile

FUCHSIN BASIC neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. May generate hydrogen, a flammable gas, in combination with strong reducing agents such as hydrides. Easily reduced to colorless leuco-bases .

Fire Hazard

Flash point data for FUCHSIN BASIC are not available, but FUCHSIN BASIC is probably combustible.

Flammability and Explosibility

Not classified

Clinical Use

Basic fuchsin is a mixture of the chlorides of rosaniline andp-rosaniline. It exists as a green crystalline powder with ametallic appearance. The compound is soluble in water andin alcohol but insoluble in ether. Basic fuchsin is a componentof carbol–fuchsin solution (Castellani’s paint), which isused topically in the treatment of fungal infections, notablyringworm and athlete’s foot.

Purification Methods

Purify the dye by dissolving it in EtOH, filtering and adding H2O. Filter or centrifuge it and wash the precipitate with Et2O and dry it in air. It has also been recrystallised from water and dried in vacuo at 40o. The crystals have a metallic green lustre. It has UV max in EtOH at 543nm ( 93,000). Its solubility in H2O is 0.26%. A carmine red colour is obtained in EtOH. It is paraRosaniline with a methyl group. [Scalan J Am Chem Soc 57 887 1937.]

Properties and Applications

TEST ITEMS	SPECIFICATION
APPEARANCE	VIOLET
LIGHTING	4-5
SOAPING	4-5
PERSPIRATING	4-5
FRICTION(DRY)	4-5
FRICTION(WET)	4
RESIDUE ON 80 MESH	5.0% max
WATER SOLUBLE	1.0% max
VOLATITE 105 °C	1.0% max
TINTING STRENGTH	100-105 %
WEIGHT METAL TOTAL	50ppm max