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HomeProduct name list(R)-(+)-Tetrahydro-2-furoic acid

(R)-(+)-Tetrahydro-2-furoic acid

  • CAS NO.:87392-05-0
  • Empirical Formula: C5H8O3
  • Molecular Weight: 116.12
  • MDL number: MFCD00211271
  • EINECS: 627-523-2
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-10-30 18:52:02
(R)-(+)-Tetrahydro-2-furoic acid Structural

What is (R)-(+)-Tetrahydro-2-furoic acid?

Description

(R)-(+)-2-Tetrahydrofuroic acid is an important pharmaceutical intermediate compound used in the preparation of β-lactam antibiotics (Faropenem sodium), influenza antiviral drugs (Baloxavir Marboxil), hypertension drugs (Terazosin), and anticancer drugs.

Chemical properties

Colorless to light yellow liquid

The Uses of (R)-(+)-Tetrahydro-2-furoic acid

(R)-(+)-2-Tetrahydrofuroic acid is a heterocyclic derivative and can be used as a pharmaceutical intermediate.

Properties of (R)-(+)-Tetrahydro-2-furoic acid

Boiling point: 128-129 °C13 mm Hg(lit.)
alpha  +19.6±0.2°(neat) (D/20℃)
Density  1.209 g/mL at 25 °C(lit.)
refractive index  n20/D 1.46(lit.)
Flash point: >230 °F
storage temp.  Keep in dark place,Sealed in dry,Room Temperature
form  clear liquid
pka 3.60±0.20(Predicted)
color  Colorless to Light yellow
optical activity [α]23/D +4°, c = 1 in methanol
BRN  4658739
CAS DataBase Reference 87392-05-0(CAS DataBase Reference)

Safety information for (R)-(+)-Tetrahydro-2-furoic acid

Signal word Danger
Pictogram(s)
ghs
Corrosion
Corrosives
GHS05
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H314:Skin corrosion/irritation
Precautionary Statement Codes P270:Do not eat, drink or smoke when using this product.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for (R)-(+)-Tetrahydro-2-furoic acid

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