(-)-Di-p-toluoyl-L-tartaric acid

Synonym(s):L-(-)-DTTA;Di-p-toluyl-L-tartaric acid

CAS NO.：32634-66-5
Empirical Formula: C20H18O8
Molecular Weight: 386.35
MDL number: MFCD00064440
EINECS: 251-131-7
SAFETY DATA SHEET (SDS)
Update Date: 2023-05-09 09:30:52

(-)-Di-p-toluoyl-L-tartaric acid Structural

What is (-)-Di-p-toluoyl-L-tartaric acid?

Chemical properties

white to light yellow crystal powde

The Uses of (-)-Di-p-toluoyl-L-tartaric acid

Inhibitor of enzyme

The Uses of (-)-Di-p-toluoyl-L-tartaric acid

Escitalopram intermediate

The Uses of (-)-Di-p-toluoyl-L-tartaric acid

(-)-O,O’-Di-p-toluoyl-L-tartaric Acid is a useful reagent for the preparation of the upadacitinib salt compound.

General Description

(-)-O,O′-Di-p-toluoyl-L-tartaric acid is a O,O′-diacyl tartaric acid derivative that can be prepared by the resolution of its racemate in the presence of cinchonine.

Properties of (-)-Di-p-toluoyl-L-tartaric acid

Melting point:	169-171 °C(lit.)
Boiling point:	432.57°C (rough estimate)
alpha	-142 º (c=10, EtOH)
Density	1.3084 (rough estimate)
refractive index	-139 ° (C=1, EtOH)
storage temp.	Store below +30°C.
solubility	Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly)
form	Crystalline Powder
pka	1.46±0.25(Predicted)
color	White to yellow
optical activity	[α]20/D 138°, c = 1 in ethanol
Water Solubility	soluble
BRN	2022481
CAS DataBase Reference	32634-66-5(CAS DataBase Reference)
EPA Substance Registry System	Butanedioic acid, 2,3-bis[(4-methylbenzoyl)oxy]-, [R-(R,R)]- (32634-66-5)

Safety information for (-)-Di-p-toluoyl-L-tartaric acid

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation
Precautionary Statement Codes	P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection.